Cavernous malformations can lead to significant neurologic symptoms - from nerve pain, weakness and coordination difficulties to visual loss, memory deficits, and speech impairment, and even extending as far as intractable epilepsy and paralysis. At 3-7% incidence in the general population is small but significant, yet the current literature does not offer comprehensive, up-to-date coverage of this condition. This volume it the HCN series is an evidence-based compendium which addresses both the scientific and clinical aspects of this unique disease process. The volume covers didactic aspects, such as the epidemiology, etiology, and diagnosis of cavernous malformations, while also providing expert clinical information on the management and treatment of these lesions. In addition, it provides coverage of modern-day advances in the genetics of cavernous malformations, as well as discussion regarding future open research questions. Readers from the laboratory bench to the bedside can expect a broad yet objective review of this pathology, with updates from the latest scientific literature and data supporting current practices. * Offers an evidence-based focus with coverage of both the scientific and clinical aspects of cavernous malformations* Addresses epidemiology, etiology, diagnosis, and genetics* Clinical insights regarding indications for surgery, surgical techniques, outcomes, and prognostic factors drawn from the authors'' extensive experiences* Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available
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Product Details
Format: Hardback
Dimensions: 191 x 235mm
Publication Date: 01 Jun 2017
Publisher: Elsevier Science & Technology
Publication City/Country: United Kingdom
Language: English
ISBN13: 9780444636287
About
Dr. Spetzler is President and Chief Executive Officer of Barrow Neurological Institute in Phoenix Arizona where he has been Director since 1986 and has held the J. N. Harber Chair of Neurological Surgery since first joining the staff in 1983. Under his guidance and focus on education research and patient care Barrow Neurological Institute has become one of the top neuroscience centers and the largest neurosurgical center in the United States with the largest neurosurgical residency training program in the country. His neurosurgical work focuses on vascular neurosurgery and skull base surgery to treat aneurysms arteriovenous malformations (AVMs) and cavernous malformations. He has developed more effective and safer neurosurgical approaches to deep areas of the brain. During his extensive surgical practice he has clipped more than 6400 aneurysms and he has developed theories on normal perfusion pressure breakthrough and how AVM size reveals the potential for rupture. He codeveloped a heuristic grading system (the Spetzler-Martin grading scale) for estimating the risk of open neurosurgery for AVMs. Dr. Spetzler is a sought-after presenter at national and international neurosurgical conferences. He has edited or coedited more than 20 books and neurosurgical atlases has published more than 700 articles in peer-reviewed academic medical journals and has coauthored more than 270 book chapters. He frequently serves as a peer reviewer of scholarly manuscripts on vascular topics. He has been editor-in-chief of the journals Operative Techniques in Neurosurgery and Skull Base: An Interdisciplinary Approach and he has been an editorial board member a section editor and an advisory board member for numerous journals. He holds chairs in Neurosurgical Education and in Neurosurgical Research at Barrow Neurological Institute and serves as a professor and executive chair of the Department of Neurosurgery at the University of Arizona College of Medicine Phoenix. He also is a past president of the American Academy of Neurological Surgery and the North American Skull Base Society and a past honorary president of the World Federation of Neurosurgical Societies Foundation. Dr. Karam Moon is a fellowship-trained cerebrovascular neurosurgeon. He completed his residency training under Dr. Robert Spetzler at the venerable Barrow Neurological Institute in Phoenix Arizona where he also completed his fellowship training in endovascular neurosurgery under Drs. Cameron G. McDougall and Felipe C. Albuquerque. He is a prolific academic neurosurgeon regularly publishing clinical outcomes studies in leading neurosurgery journals and speaking at national conferences throughout the year.