{"product_id":"a-practical-approach-to-quantitative-validation-of-patient-reported-outcomes-a-simulation-based-guide-using-sas","title":"Practical Approach to Quantitative Validation of Patient-Reported Outcomes","description":"\u003cp\u003e\u003cb\u003eA Simulation-Based Guide Using SAS\u003c\/b\u003e\u003cbr\u003eIn \u003ci\u003eA Practical Approach to Quantitative Validation of Patient-Reported Outcomes\u003c\/i\u003e, two distinguished researchers, with 50 years of collective research experience and hundreds of publications on patient-centered research, deliver a detailed and comprehensive exposition on the critical steps required for quantitative validation of patient-reported outcomes (PROs). The book provides an incisive and instructional explanation and discussion on major aspects of psychometric validation methodology on PROs, especially relevant for medical applications sponsored by the pharmaceutical industry, where SAS is the primary software, and evaluated in regulatory and other healthcare environments.\u003c\/p\u003e \u003cp\u003eCentral topics include test-retest reliability, exploratory and confirmatory factor analyses, construct and criterion validity, responsiveness and sensitivity, interpretation of PRO scores and findings, and meaningful within-patient change and clinical important difference. The authors provide step-by-step guidance while walking readers through how to structure data prior to a PRO analysis and demonstrate how to implement analyses with simulated examples grounded in real-life scenarios.\u003c\/p\u003e \u003cp\u003eReaders will also find:\u003c\/p\u003e \u003cul\u003e\n\u003cli\u003eA thorough introduction to patient-reported outcomes, including their definition, development, and psychometric validation\u003c\/li\u003e\n\u003cli\u003eComprehensive explorations of the validation workflow, including discussions of clinical trials as a data source for validation and the validation workflow for single and multi-item scales\u003c\/li\u003e\n\u003cli\u003eIn-depth discussions of key concepts related to a validation of a measurement scale\u003c\/li\u003e\n\u003cli\u003eSpecial attention is given to the US Food and Drug Administration (FDA) guidance on development and validation of the PROs, which lay the foundation and inspiration for the analytic methods executed\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eA Practical Approach to Quantitative Validation of Patient-Reported Outcomes\u003c\/i\u003e is a required reference that will benefit psychometricians, statisticians, biostatisticians, epidemiologists, health service and public health researchers, outcome research scientists, regulators, and payers.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSTATISTICS IN PRACTICE\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eA series of practical books outlining the use of statistical techniques in a wide range of applications areas:\u003c\/p\u003e \u003cul\u003e\n\u003cli\u003e\u003cb\u003eHUMAN AND BIOLOGICAL SCIENCES\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003eEARTH AND ENVIRONMENTAL SCIENCES\u003c\/li\u003e\n\u003cli\u003eINDUSTRY, COMMERCE AND FINANCE\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49787561312600,"sku":"9781119376378","price":104.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0278\/1295\/4195\/files\/9781119376378_32f0fda5-7fb0-4373-8ea9-fef1147ad653.jpg?v=1780392653","url":"https:\/\/agendabookshop.com\/products\/a-practical-approach-to-quantitative-validation-of-patient-reported-outcomes-a-simulation-based-guide-using-sas","provider":"Agenda Bookshop","version":"1.0","type":"link"}