{"product_id":"compendium-of-in-vivo-monitoring-in-real-time-molecular-neuroscience-volume-2-microdialysis-and-sensing-of-neural-tissues","title":"Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 2: Microdialysis And Sensing Of Neural Tissues","description":"Volume 1 of this series focused mainly on small molecules which are intrinsically electroactive. Volume 2 continues to provide current approaches to real time measurements of essential species in the central nervous system. It describes microdialysis, a sampling technique, which facilitates the removal of small volumes of solution containing the analyte(s) of interest which can be subsequently separated by chromatography and analyzed by a range of techniques. These include electrochemistry, UV-Vis spectroscopy, fluorescence and mass spectroscopy. This approach affords the opportunity to measure a range of targets in real-time thus providing access to pharmacokinetic\/pharmacodynamics measurements affording the possibility of measuring the disappearance of a drug after administration and the subsequent appearance of metabolites. Microdialysis further affords the ability to sample peptides and proteins of neurobiological interest.Consistent with the goals of Volume 1, Volume 2 seeks to provide for scientists in the field of neurobiology a base of bioanalytical techniques that may not be familiar to them. Specific examples are provided and the fundamental basis of the technique is also covered.","brand":"World Scientific Publishing Co Pte Ltd","offers":[{"title":"Default Title","offer_id":54235536359768,"sku":"9789813220539","price":183.52,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0278\/1295\/4195\/files\/9789813220539_3781573c-cc21-45ce-8d02-420a59e1d8a2.jpg?v=1777266059","url":"https:\/\/agendabookshop.com\/products\/compendium-of-in-vivo-monitoring-in-real-time-molecular-neuroscience-volume-2-microdialysis-and-sensing-of-neural-tissues","provider":"Agenda Bookshop","version":"1.0","type":"link"}