{"product_id":"design-and-analysis-of-non-inferiority-trials","title":"Design and Analysis of Non-Inferiority Trials","description":"\u003cp\u003eThe increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Using examples from real clinical trials, \u003cstrong\u003eDesign and Analysis of Non-Inferiority Trials\u003c\/strong\u003e brings together this body of research and confronts the issues involved in the design of a non-inferiority trial. Each chapter begins with a non-technical introduction, making the text easily understood by those without prior knowledge of this type of trial. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTopics covered include:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e \u003c\/p\u003e \u003c\/li\u003e\n\u003cli\u003eA variety of issues of non-inferiority trials, including multiple comparisons, missing data, analysis population, the use of safety margins, the internal consistency of non-inferiority inference, the use of surrogate endpoints, trial monitoring, and equivalence trials\u003c\/li\u003e\n\u003cli\u003eSpecific issues and analysis methods when the data are binary, continuous, and time-to-event\u003c\/li\u003e\n\u003cli\u003eThe history of non-inferiority trials and the design and conduct considerations for a non-inferiority trial\u003c\/li\u003e\n\u003cli\u003eThe strength of evidence of an efficacy finding and how to evaluate the effect size of an active control therapy\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eA comprehensive discussion on the purpose and issues involved with non-inferiority trials, \u003cstrong\u003eDesign and Analysis of Non-inferiority Trials\u003c\/strong\u003e will assist current and future scientists and statisticians on the optimal design of non-inferiority trials and in assessing the quality of non-inferiority comparisons done in practice.\u003c\/p\u003e","brand":"Taylor \u0026 Francis Inc","offers":[{"title":"Default Title","offer_id":54257136501080,"sku":"9781584888048","price":192.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0278\/1295\/4195\/files\/9781584888048.jpg?v=1768332625","url":"https:\/\/agendabookshop.com\/products\/design-and-analysis-of-non-inferiority-trials","provider":"Agenda Bookshop","version":"1.0","type":"link"}