{"product_id":"dynamic-force-spectroscopy-and-biomolecular-recognition-1","title":"Dynamic Force Spectroscopy and Biomolecular Recognition","description":"\u003cp\u003eMolecular recognition, also known as biorecognition, is the heart of all biological interactions. Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies and is finding wider applications in areas such as biophysics and polymer science. In six chapters, \u003cstrong\u003eDynamic Force Spectroscopy and Biomolecular Recognition\u003c\/strong\u003e covers the most recent ideas and advances in the field of DFS applied to biorecognition:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e \u003c\/p\u003e \u003c\/li\u003e\n\u003cli\u003e \u003cem\u003eChapter 1:\u003c\/em\u003e Reviews the basic and novel aspects of biorecognition and discusses the emerging capabilities of single-molecule techniques to disclose kinetic properties and molecular mechanisms usually hidden in bulk measurements\u003c\/li\u003e\n\u003cli\u003e \u003cem\u003eChapter 2:\u003c\/em\u003e Describes the basic principle of atomic force microsocopy (AFM) and DFS, with particular attention to instrumental and theoretical aspects more strictly related to the study of biomolecules\u003c\/li\u003e\n\u003cli\u003e \u003cem\u003eChapter 3:\u003c\/em\u003e Overviews the theoretical background in which experimental data taken in nonequilibrum measurements of biomolecular unbinding forces are extrapolated to equilibrium conditions\u003c\/li\u003e\n\u003cli\u003e \u003cem\u003eChapter 4:\u003c\/em\u003e Reviews the most common and efficient strategies adopted in DFS experiments to immobilize the interacting biomolecules to the AFM tip and to the substrate\u003c\/li\u003e\n\u003cli\u003e \u003cem\u003eChapter 5:\u003c\/em\u003e Presents and discusses the most representative aspects related to the analysis of DFS data and the challenges of integrating well-defined criteria to calibrate data in automatic routinary procedures \u003c\/li\u003e\n\u003cli\u003e \u003cem\u003eChapter 6\u003c\/em\u003e\u003cstrong\u003e:\u003c\/strong\u003e Overviews the most relevant DFS applications to study biorecognition processes, including the biotin\/avidin pair, and selected results on various biological complexes, including antigen\/antibody, proteins\/DNA, and complexes involved in adhesion processes \u003c\/li\u003e\n\u003cli\u003e \u003cem\u003eChapter 7\u003c\/em\u003e\u003cstrong\u003e:\u003c\/strong\u003e Summarizes the main results obtained by DFS applied to study biorecognition processes with forthcoming theoretical and experimental advances\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAlthough DFS is a widespread, worldwide technique, no books focused on this subject have been available until now. \u003cstrong\u003eDynamic\u003c\/strong\u003e \u003cstrong\u003eForce Spectroscopy and Biomolecular Recognition\u003c\/strong\u003e provides the state of the art of experimental data analysis and theoretical procedures, making it a useful tool for researchers applying DFS to study biorecognition processes.\u003c\/p\u003e","brand":"Taylor \u0026 Francis Inc","offers":[{"title":"Default Title","offer_id":54260166492504,"sku":"9781439862377","price":210.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0278\/1295\/4195\/files\/9781439862377.jpg?v=1779342353","url":"https:\/\/agendabookshop.com\/products\/dynamic-force-spectroscopy-and-biomolecular-recognition-1","provider":"Agenda Bookshop","version":"1.0","type":"link"}