{"product_id":"inducing-targeted-protein-degradation","title":"Inducing Targeted Protein Degradation","description":"\u003cb\u003eInducing Targeted Protein Degradation\u003c\/b\u003e \u003cp\u003e\u003cb\u003eEnables drug developers in academia and industry to expand the range of accessible drug targets through induced protein degradation\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eSince the breakthrough of the PROTAC technology in 2015, targeted protein degradation has revolutionized drug discovery, enabling pharma companies to develop completely novel therapeutics. \u003ci\u003eInducing Targeted Protein Degradation\u003c\/i\u003e is a timely guide to navigating the complexities of the subject and understanding its practical application, with an eye on expanding the druggable space.  \u003c\/p\u003e\u003cp\u003eIn \u003ci\u003eInducing Targeted Protein Degradation\u003c\/i\u003e, readers will find the most recent information on:  \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eCellular mechanisms of targeted protein degradation and current approaches \tto utilize these mechanisms for drug discovery \u003c\/li\u003e\n\u003cli\u003eA comparison of different induced degradation approaches, including PROTAC, molecular glues, LYTACs and ATTECs as well as additional post translational modifications\u003c\/li\u003e\n\u003cli\u003eDrug development aspects such as DMPK optimization and criteria for the selection of clinical candidates\u003c\/li\u003e\n\u003cli\u003eA discussion of the potential of targeted degradation for expanding the druggable space\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e  \u003c\/p\u003e\u003cp\u003e\u003ci\u003eInducing Targeted Protein Degradation\u003c\/i\u003e will serve as a practice-oriented reference on induced protein degradation for drug discovery professionals and for researchers employing chemical biology approaches.\u003c\/p\u003e","brand":"Wiley-VCH Verlag GmbH","offers":[{"title":"Default Title","offer_id":54254658617688,"sku":"9783527350131","price":137.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0278\/1295\/4195\/files\/9783527350131.jpg?v=1778551230","url":"https:\/\/agendabookshop.com\/products\/inducing-targeted-protein-degradation","provider":"Agenda Bookshop","version":"1.0","type":"link"}