{"product_id":"mizoroki-heck-reaction","title":"Mizoroki-Heck Reaction","description":"Exploring the importance of Richard F. Heck’s carbon coupling reaction, this book highlights the subject of the 2010 Nobel Prize in Chemistry for palladium-catalyzed cross couplings in organic synthesis, and includes a foreword from Nobel Prize winner Richard F. Heck.  \u003cp\u003eThe Mizoroki-Heck reaction is a palladium-catalyzed carbon–carbon bond forming process which is widely used in organic and organometallic synthesis. It has seen increasing use in the past decade as chemists look for strategies enabling the controlled construction of complex carbon skeletons. \u003ci\u003eThe Mizoroki-Heck Reaction\u003c\/i\u003e is the first dedicated volume on this important reaction, including topics on:\u003c\/p\u003e \u003cul\u003e\n\u003cli\u003emechanisms of the Mizoroki-Heck reaction\u003c\/li\u003e\n\u003cli\u003eintermolecular Mizoroki-Heck reactions\u003c\/li\u003e\n\u003cli\u003efocus on regioselectivity and product outcome in organic synthesis\u003c\/li\u003e\n\u003cli\u003ewaste-minimized Mizoroki-Heck reactions\u003c\/li\u003e\n\u003cli\u003eintramolecular Mizoroki-Heck reactions\u003c\/li\u003e\n\u003cli\u003eformation of heterocycles\u003c\/li\u003e\n\u003cli\u003echelation-controlled Mizoroki-Heck reactions\u003c\/li\u003e\n\u003cli\u003ethe Mizoroki-Heck reaction in domino processes\u003c\/li\u003e\n\u003cli\u003eoxidative heck-type reactions (Fujiwara-Moritani reactions)\u003c\/li\u003e\n\u003cli\u003eMizoroki-Heck reactions with metals other than palladium\u003c\/li\u003e\n\u003cli\u003eligand design for intermolecular asymmetric Mizoroki-Heck reactions\u003c\/li\u003e\n\u003cli\u003eintramolecular enantioselective Mizoroki-Heck reactions\u003c\/li\u003e\n\u003cli\u003edesymmetrizing Mizoroki-Heck reactions\u003c\/li\u003e\n\u003cli\u003eapplications in combinatorial and solid phase syntheses, and the development of modern solvent systems and reaction techniques\u003c\/li\u003e\n\u003cli\u003ethe asymmetric intramolecular Mizoroki-Heck reaction in natural product total synthesis\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003eSeveral chapters are devoted to asymmetric Heck reactions with particular focus on the construction of otherwise difficult-to-obtain sterically congested tertiary and quaternary carbons. Industrial and academic applications are highlighted in the final section. \u003ci\u003eThe Mizoroki-Heck Reaction\u003c\/i\u003e will find a place on the bookshelves of any organic or organometallic chemist.\u003c\/p\u003e \u003cp\u003e“I am convinced that this book will rapidly become the most important reference text for research chemists in academia and industry who seek orientation in the rapidly growing and – for the layman – confusing field described as the “’Mizoroki–Heck reaction’.” (\u003ci\u003eSynthesis\u003c\/i\u003e, March 2010)\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":54231660036440,"sku":"9780470033944","price":195.86,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0278\/1295\/4195\/files\/9780470033944.jpg?v=1778543134","url":"https:\/\/agendabookshop.com\/products\/mizoroki-heck-reaction","provider":"Agenda Bookshop","version":"1.0","type":"link"}