{"product_id":"physiologically-based-pharmacokinetic-pbpk-modeling-and-simulations","title":"Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations","description":"\u003cb\u003ePhysiologically Based Pharmacokinetic (PBPK) Modeling and Simulations\u003c\/b\u003e \u003cp\u003e\u003cb\u003eThe first book dedicated to the emerging field of physiologically based pharmacokinetic modeling (PBPK)\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eNow in its second edition, \u003ci\u003ePhysiologically Based Pharmacokinetic (PBPK) Modelling and  Simulations: Principles, Methods, and Applications in the Pharma Industry\u003c\/i\u003e remains the premier reference book throughout the rapidly growing PBPK user community. Using clear and concise language, author Sheila Annie Peters connects theory with practice as she explores the vast potential of PBPK modeling for improving drug discovery and development. \u003c\/p\u003e\u003cp\u003eThis fully updated new edition covers key developments in the field of PBPK modelling and simulations that have emerged in recent years. A brand-new section provides case studies in different application areas of PBPK modelling, including drug-drug interaction, genetic polymorphism, renal impairment, and pediatric extrapolation. Additional chapters address  topics such as model-informed drug development (MIDD) and expose readers to a wide range of  current applications in the field. Throughout the book, substantially revised  chapters simplify complex topics and offer a balanced view of both the opportunities and challenges of PBPK modelling. Providing timely and comprehensive coverage of one of the most exciting new areas of pharmaceutical science, this book: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eDescribes the principles behind physiological modeling of pharmacokinetic processes, inter-individual variability, and drug interactions for small molecule drugs and biologics\u003c\/li\u003e\n\u003cli\u003eFeatures a wealth of new figures and case studies of the applications of PBPK modelling along the value chain in drug discovery and development\u003c\/li\u003e\n\u003cli\u003eReflects the latest regulatory guidelines on the reporting of PBPK modelling analysis\u003c\/li\u003e\n\u003cli\u003eIncludes access to a new companion website containing code, datasets, explanations of case examples in the text, and discussion of key developments in the field\u003c\/li\u003e\n\u003cli\u003eContains a brief overview of the field, end-of-chapter keywords for easy reference, and an extensive bibliography\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003ePhysiologically Based Pharmacokinetic (PBPK) Modeling and Simulations: Principles, Methods, and Applications in the Pharmaceutical Industry, Second Edition\u003c\/i\u003e is an indispensable ­single-volume resource for beginning and intermediate practitioners across the pharmaceutical sciences in both industry and academia.\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Product","offer_id":54217966551384,"sku":"9781119497684","price":189.66,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0278\/1295\/4195\/files\/9781119497684__67c1e23024283_1fc4f208-1de5-411a-a252-07ff18f122b1.jpg?v=1741157316","url":"https:\/\/agendabookshop.com\/products\/physiologically-based-pharmacokinetic-pbpk-modeling-and-simulations","provider":"Agenda Bookshop","version":"1.0","type":"link"}