{"product_id":"structural-biology-in-drug-discovery","title":"Structural Biology in Drug Discovery","description":"\u003cp\u003eWith the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, \u003ci\u003eStructural Biology in Drug Discovery: Methods, Techniques, and Practices\u003c\/i\u003e describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field.\u003cbr\u003e\u003cbr\u003eThe combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that:\u003c\/p\u003e \u003cul\u003e\n\u003cli\u003ePresents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology\u003c\/li\u003e\n\u003cli\u003eIncludes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design\u003c\/li\u003e\n\u003cli\u003eEmphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures\u003c\/li\u003e\n\u003cli\u003eIllustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Product","offer_id":54222664368472,"sku":"9781118681015","price":291.34,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0278\/1295\/4195\/files\/9781118681015__67c1fab1d2566_c340240e-abee-482a-9556-585e59251f14.jpg?v=1741160437","url":"https:\/\/agendabookshop.com\/products\/structural-biology-in-drug-discovery","provider":"Agenda Bookshop","version":"1.0","type":"link"}