A01=Felix Mitelman
A01=Sverre Heim
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Author_Felix Mitelman
Author_Sverre Heim
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cancer cytogenetic applications
Cancer cytogenetic history
cancer cytogenetic technology
cancer cytogeneticclassification
cancer cytogenetics impact
cancer cytogenetics influence
cancer cytogeneticstructure
Category1=Non-Fiction
Category=PS
COP=United Kingdom
Delivery_Delivery within 10-20 working days
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future of cancer cytogenetics
Language_English
PA=Available
Price_€100 and above
PS=Active
softlaunch
Product details
- ISBN 9781119651987
- Weight: 454g
- Dimensions: 170 x 244mm
- Publication Date: 10 Mar 2022
- Publisher: John Wiley and Sons Ltd
- Publication City/Country: GB
- Product Form: Hardback
- Language: English
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Explore the past, present, and future of cancer cytogenetics
In Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics, globally renowned researchers Drs. Sverre Heim and Felix Mitelman deliver a state-of-the-art review of how cancer cytogenetic analyses have contributed to an improved understanding of tumorigenesis as well as to the diagnosis and treatment of cancer patients. The book also discusses how cytogenetics – the study of chromosomes - meets, interacts with, and cross-fertilizes other investigative technologies, including molecular somatic cell genetics.
The book provides an impetus to think more deeply about the role chromosomes, and their abnormalities, play in health and disease, especially in neoplastic disorders. From which origins did cytogenetics develop? How did the finding of acquired chromosomal abnormalities in cells of leukemias and solid tumors influence our understanding of cancer as a biological process? How was information of this nature put to good use in the clinical management of cancer patients?
Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics offers readers:
In Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics, globally renowned researchers Drs. Sverre Heim and Felix Mitelman deliver a state-of-the-art review of how cancer cytogenetic analyses have contributed to an improved understanding of tumorigenesis as well as to the diagnosis and treatment of cancer patients. The book also discusses how cytogenetics – the study of chromosomes - meets, interacts with, and cross-fertilizes other investigative technologies, including molecular somatic cell genetics.
The book provides an impetus to think more deeply about the role chromosomes, and their abnormalities, play in health and disease, especially in neoplastic disorders. From which origins did cytogenetics develop? How did the finding of acquired chromosomal abnormalities in cells of leukemias and solid tumors influence our understanding of cancer as a biological process? How was information of this nature put to good use in the clinical management of cancer patients?
Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics offers readers:
- A thorough introduction to ancient theories of disease, the advent of cellular pathology, and how a scientific interest in chromosomes developed
- Comprehensive exploration of the conceptual importance of Theodor Boveri and his somatic mutation theory of cancer
- A detailed chronological resume of cancer cytogenetic discoveries during the 20th century
- In-depth discussions of the role of chromosome abnormalities, oncogenes, and tumor suppressor genes in leukemias, lymphomas, and solid tumors, together with a survey of what chromosome analyses have revealed about the clonal evolution of neoplastic cell populations
- A discussion of the importance of pathogenetic classifications of neoplastic diseases, the role chromosome abnormalities play in this context, and which technological breakthroughs can be expected in chromosome-oriented cancer research
