Advanced Practical Organic Chemistry

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13C NMR Spectrum
A01=Barry Lygo
A01=Garry Procter
A01=John Leonard
advanced organic synthesis techniques
Author_Barry Lygo
Author_Garry Procter
Author_John Leonard
Category=PNN
chemical literature search
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experimental protocols chemistry
FEP Tubing
Filter Thimble
Flash Chromatography
Gas Burette
Gas Tight Syringes
Gases
Grignard Reagents
High Vacuum Pump
Inert Gas
Jacketed Vessels
Kugelrohr Apparatus
Laboratory equipment
laboratory safety procedures
Large-scale reactions
Larger Scale Reactions
Magnetic Stirrer Hot Plates
MPLC System
NMR Experiment
NMR Spectrum
NMR Tube
Organic synthesis
Pressure Equalizing Dropping Funnel
PTFE Stopcock
Purification
Reaction Flask
reagent preparation methods
Reagents
Record NMR Spectrum
Rotary Oil Pump
Round Bottom Flasks
Seal NMR Tube
Small-scale reactions
solvent purification techniques
Solvents
TLC Plate
vacuum line operation
Vacuum pumps

Product details

  • ISBN 9781439860977
  • Weight: 580g
  • Dimensions: 156 x 234mm
  • Publication Date: 08 Jan 2013
  • Publisher: Taylor & Francis Inc
  • Publication City/Country: US
  • Product Form: Paperback
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Any research that uses new organic chemicals, or ones that are not commercially available, will at some time require the synthesis of such compounds. Therefore, organic synthesis is important in many areas of both applied and academic research, from chemistry to biology, biochemistry, and materials science. The third edition of a bestseller, Advanced Practical Organic Chemistry is a guide that explains the basic techniques of organic chemistry, presenting the necessary information for readers to carry out widely used modern organic synthesis reactions. This book is written for advanced undergraduate and graduate students as well as industrial organic chemists, particularly those involved in pharmaceutical, agrochemical, and other areas of fine chemical research. It provides the novice or nonspecialist with the often difficult-to-find information on reagent properties needed to perform general techniques. With over 80 years combined experience training and developing organic research chemists in industry and academia, the authors offer sufficient guidance for researchers to perform reactions under conditions that give the highest chance of success, including the appropriate precautions to take and proper experimental protocols. The text also covers the following topics:

  • Record keeping and equipment
  • Solvent purification and reagent preparation
  • Using gases and working with vacuum pumps
  • Purification, including crystallization and distillation
  • Small-scale and large-scale reactions
  • Characterization, including NMR spectra, melting point and boiling point, and microanalysis
  • Efficient ways to find information in the chemical literature

With fully updated text and all newly drawn figures, the third edition provides a powerful tool for building the knowledge on the most up-to-date techniques commonly used in organic synthesis.

John Leonard is currently a principal scientist at AstraZeneca Pharmaceuticals, where he is primarily involved with synthetic route design and development activities. Prior to this he was a professor of organic chemistry at the University of Salford, UK.Garry Procter is a professor and director of teaching in the School of Chemistry at the University of Manchester, UK. Before this he was director of undergraduate laboratories in the Department of Chemistry and Chemical Biology at Harvard University.Barry Lygo is currently a professor of chemistry at the University of Nottingham, UK, working in the field of asymmetric catalysis and synthesis.

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