Asymmetric Synthesis Of 3, 3-disubstituted Oxindoles
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A01=Helene Pellissier
A01=Ramon Rios Torres
A01=Renato Dalpozzo
A01=Swapandeep Singh Chimni
Author_Helene Pellissier
Author_Ramon Rios Torres
Author_Renato Dalpozzo
Author_Swapandeep Singh Chimni
Biochemistry
Category=PNN
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Organic Chemistry
Oxindoles
Spirocycles
Synthesis
Product details
- ISBN 9781786347299
- Publication Date: 18 Sep 2019
- Publisher: World Scientific Europe Ltd
- Publication City/Country: GB
- Product Form: Hardback
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Indole derivatives are the most common heterocycle compounds present in nature, for this reason, they have been referred to as "privileged structures". In fact, many approved drugs — and natural products — belong to this family. Among indole derivatives, oxindoles have a structural complexity, which have stimulated generations of synthetic chemists to design strategies for assembling these structures, and their enantioselective synthesis is still growing.This book proposes to describe the known enantioselective syntheses of oxindole derivatives. It is divided in six chapters each referring to a specific class of asymmetric oxindole derivatives. After the introduction, Chapter 2 describes all-carbon spirooxindoles; Chapter 3, open chain 3,3-dialkyloxindoles; Chapter 4, 3-substituted-3-aminooxindoles; Chapter 5, 3-substituted-3-hydroxyoxindoles; Chapter 6, 3-hetero-3-substituted oxindoles. It will be a useful tool for synthetic chemists, who assemble total synthesis of natural products, as well as for drug discovery chemists either in academic or in industry R&S laboratories.
