Adenosine Monophosphate Activated Protein Kinase
age-related pathologies
Amp Activate Protein Kinase
AMPK
Andre Du Toit
ATG Protein
ATP Availability
Autophagic Flux
Autophagic Marker LC3
Autophagosomal Membrane
Autophagosome Formation
autophagy signaling in disease
Ben Loos
Category=PSC
Category=PSD
Category=PSF
cell death
cellular homeostasis
cellular senescence research
cellular signaling pathways
Chaperone Mediated Autophagy
Cheng Bing
Chrisna Swart
Ciliary Length
CMA Activity
CMA Substrate
David Sulzer
eq_bestseller
eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
eq_science
Grace G.Y. Lim
Guomei Tang
Han Xie
Han-Ming Shen
Hui-Ying Chan
immune system regulation
Kah-Leong Lim
Karen Crasta
LC3 Lipidation
Lipid Droplet Surface
Lipid Droplets
lysosomal function
Ma Activity
metabolic adaptation
molecular pathways
Moumita Rakshit
neurodegenerative mechanisms
Nuria Martinez-Lopez
Olatz Pampliega
Patrice Codogno
PC
Protein Inclusions
Protein Kinase
Rut Valdor
Sheng-Han Kuo
Sijie Tan
Tassula Proikas-Cezanne
Theresia Zuleger
TSC2 Complex
TSC2 Deficient Cell
Tso-Pang Yao
Ubiquitinated Protein Aggregates
ULK Complex
Vps34 Complex
Yi Ren
Product details
- ISBN 9780367657727
- Weight: 557g
- Dimensions: 156 x 234mm
- Publication Date: 30 Mar 2021
- Publisher: Taylor & Francis Ltd
- Publication City/Country: GB
- Product Form: Paperback
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Autophagy and Signaling is an up-to-date overview of the many signaling pathways regulating autophagy in response to different cellular needs. Discussion includes the status and future directions of autophagy signaling research with respect to different aspects of health and disease. These include the roles of autophagy in regulating cell fate, immune response and host defense, nutrient sensing and metabolism, neural functions and homeostasis. The mechanisms and significance of cross-talk between autophagy and other cellular processes is also explored. Lastly, alterations in autophagy observed in aging and age-related pathologies are described.
Esther Wong graduated from the National University of Singapore with her PhD in 2004. She is an Assistant Professor with the School of Biological Sciences at Nanyang Technological University in Singapore. Her research focuses on autophagy, a cellular quality control pathway involved in protein degradation by lysosomes. The overall goal is to elucidate yet unknown mechanisms in the degradation of proteins by autophagy and how the related defects result in accumulation of damaged components, proteotoxicity and loss of cognitive functions associated with neurodegeneration and aging.
