Biotic Type Antioxidants: the prospective search area for novel chemical drugs

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A01=E A. Parfenov
A01=Gennady Zaikov
A01=Parfenov
antioxidant drug development applications
antitumour mechanisms
Author_E A. Parfenov
Author_Gennady Zaikov
Author_Parfenov
Cardiovascular Clinics
Category=PSB
Complex Compounds
copper chelation therapy
Dihydrolipoic Acid
Effective Chelators
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Ethyl Acetoacetate
Kojic Acid
Lipoic Acid
Nsaid Class
oxidative stress research
Physiologically Compatible
redox biochemistry
superoxide dismutase models
trace element nutrition

Product details

  • ISBN 9789067643085
  • Weight: 1315g
  • Dimensions: 178 x 254mm
  • Publication Date: 25 May 2000
  • Publisher: Brill
  • Publication City/Country: NL
  • Product Form: Hardback
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The discovery of molecular and cellular mechanisms of pathology, together with the present data on drug treatment result in enhanced drug design and testing. The known mechanisms of biological activity as displayed by ascorbic acid and other natural reductones are the reason that they are considered to be physiologically compatible antioxidants, many of which are trace elements in food. The pharmacological potential of natural antioxidants may be enhanced by chemical modification.

Biotic antioxidants possess an important potential to be a reliable basis of the development of new multipurpose drugs, within the framework of existing technological structures.

This book shows approaches for possible use of these natural antioxidants. In particular, such an approach is described for the case of the design of superoxide dismutase models with anti-tumour activity.

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