A01=Alberto Cambrosio
A01=Peter Keating
Author_Alberto Cambrosio
Author_Peter Keating
biomedicine
cancer
Category=MJCL
chemotherapy
clinical trials
data
diagnosis
discovery
disease
doctors
drugs
eq_isMigrated=1
eq_nobargain
ethics
gleevec
healthcare
innovation
leukemia
medicine
molecular biology
nonfiction
oncogenes
oncologists
oncology
oncoproteins
patients
pharmaceuticals
radiation
radiotherapy
randomization
regimens
research
science
screening
statistical significance
surgery
targeted therapy
terminal illness
treatment
vamp trial
Product details
- ISBN 9780226428918
- Weight: 765g
- Dimensions: 16 x 24mm
- Publication Date: 01 Feb 2012
- Publisher: The University of Chicago Press
- Publication City/Country: US
- Product Form: Hardback
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Until the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians loath to assign patients randomly to competing treatments. And yet today these trials form the basis of medical oncology. How did such a spectacular change occur? And how did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine? In "Cancer on Trial" Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the clinical cancer trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology.
A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.
Peter Keating is professor of history at the Universite du Quebec a Montreal. Alberto Cambrosio is professor in the Department of Social Studies of Medicine at McGill University. Together, they are the authors of Exquisite Specificity: The Monoclonal Antibody Revolution and Biomedical Platforms: Realigning the Normal and the Pathological in Late Twentieth-Century Medicine.
