Cellular and Molecular Biology of Metals

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A01=D. James Koropatnick
A01=Rudolfs K. Zalups
advanced metal ion transport mechanisms
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Author_D. James Koropatnick
Author_Rudolfs K. Zalups
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Basolateral Membrane
Category1=Non-Fiction
Category=PSB
Category=PSBT
Category=PSD
Category=PSF
cell biology
cellular signaling pathways
cking
COP=United States
Delivery_Delivery within 10-20 working days
DNA Methylation
eq_bestseller
eq_isMigrated=2
eq_nobargain
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eq_science
essential and toxic metal disposition
Free Zinc Ions
Gap Junction
GSH Status
heavy metal detoxification
heme
Hg2
High Af Nity
higher
homeostasis
immune system modulation
Inorganic Mercury
Language_English
LLC PK1 Cell
Low Molecular Weight Thiol
Luminal Plasma Membrane
Mercuric Ions
Mercuric Species
metabolism
metal homeostasis
Metal Ion
metalloprotein function
Mn Transport
molecular biology
nity
Organic Anion
oxidative
oxygenase
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Price_€100 and above
proximal
Proximal Tubular Epithelial Cells
Proximal Tubules
PS=Active
PT
PT Cell
Renal Accumulation
Renal GSH
renal physiology
role of metals in enzymatic processes
Sinusoidal Membrane
softlaunch
stress
Tf Receptor
toxicology research
traf
Traf Cking
transcriptional regulation
transport of metals by target cells
tubule

Product details

  • ISBN 9781420059977
  • Weight: 954g
  • Dimensions: 178 x 254mm
  • Publication Date: 21 May 2010
  • Publisher: Taylor & Francis Inc
  • Publication City/Country: US
  • Product Form: Hardback
  • Language: English
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With chapter contributions from more than 30 metal biology experts, Cellular and Molecular Biology of Metals explains the role of key divalent metal ions involved in the molecular and cellular biology of various target cell populations. Although it primarily focuses on homeostatic metals, such as nickel, zinc, and chromium, the text also discusses a few environmentally pertinent, toxic divalent cations, including mercury, cadmium, and arsenic.

This authoritative resource reviews the physiological mechanisms underlying the handling of essential and toxic metal ions, including metal ion homeostasis, metals and enzyme activity, metals and transcriptional regulation, and metal ion transport. It also analyzes other functions designed to avoid metal-induced toxicity and mediate the metal enhancement of cellular function.

The role of metal ions and their effect on mammalian cells and organs are only beginning to be truly defined. Cellular and Molecular Biology of Metals arms metals toxicologists and cellular and molecular biologists with the necessary knowledge they need to take the research effort to the next level.

Rudolfs K. Zalups, PhD, trained as a fellow and instructor at the Mayo Clinic, Yale University School of Medicine, University of Maryland School of Medicine, and the University of Rochester School of Medicine and Dentistry. He is now a professor at the Mercer University School of Medicine in Macon, Georgia.
James Koropatnick, PhD, is a Distinguished Oncology Scientist, Director of the LRCP Cancer Research Laboratory Program, Director of the UWO/CIHR Strategic Training Program in Cancer Research and Technology Transfer, Assistant Director of the Lawson Health Research Institute, and a Full Professor in the UWO Department of Oncology with cross-appointments in the UWO Departments of Microbiology and Immunology, Physiology and Pharmacology, and Pathology. He is also the Chief Scientific Officer of Sarissa, Inc. (a biotech discovery company) and sits on the Advisory Boards of Critical Outcomes Therapeutics, Inc., ID Laboratories, Inc., and MedVax Pharma, Inc.

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