A01=Greg J. Barritt
Author_Greg J. Barritt
Category=PSF
Category=PSV
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Product details
- ISBN 9780198547266
- Weight: 787g
- Dimensions: 187 x 244mm
- Publication Date: 09 Apr 1992
- Publisher: Oxford University Press
- Publication City/Country: GB
- Product Form: Paperback
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This textbook brings together and puts into perspective current knowledge of intra-cellular signalling systems within animals. The ordered growth and functioning of animal cells requires the transfer of information from one part of the cell to another. This information comes from a variety of sources, both within and outside the cell. Hormones, neurotransmitters, growth factors and extra-cellular metabolites interact with specific receptors on the plasma membrane or in the cytoplasm. Inside the cell, information is relayed by intra-cellular messengers including cyclic nucleotides, inositol polyphosphates, diacylglycerol and calcium, GTP-binding proteins, protein kinases and DNA-binding proteins. Finely balanced interactions between these different signalling pathways ensure that the required response occurs and abnormalities in any of the components of the system can lead to a variety of diseases, including cancer.
