Computational Biology

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A01=Ralf Blossey
American Chemical Society
Author_Ralf Blossey
biological networks
biomolecular systems
Category=PHVN
Category=PS
Category=UY
complex interaction networks
computational biology
Cooperativity Parameter
Debye Screening Length
Degree Distribution
DNA Hairpin
DNA Make
Drug DNA Complex
eq_bestseller
eq_computing
eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
eq_science
Fluctuation Theorem
genomic revolution
Gillespie Algorithm
Ginzburg Landau Theory
Histone Tail
Histone Tail Modifications
human genome
Ising Model
Langevin Equation
Master Equation
Minimal Free Energy Structure
Non-equilibrium Statistical Mechanics
Nonequilibrium Statistical Mechanics
Nucleosomal Core Particle
Ordinary Differential Equations
Partition Function
Poisson Boltzmann Equation
Poisson Boltzmann Theory
Random Graph
Spectral Abscissae
statistical mechanics

Product details

  • ISBN 9780367779740
  • Weight: 449g
  • Dimensions: 156 x 234mm
  • Publication Date: 31 Mar 2021
  • Publisher: Taylor & Francis Ltd
  • Publication City/Country: GB
  • Product Form: Paperback
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Computational biology has developed rapidly during the last two decades following the genomic revolution which culminated in the sequencing of the human genome. More than ever it has developed into a field which embraces computational methods from different branches of the exact sciences: pure and applied mathematics, computer science, theoretical physics. This Second Edition provides a solid introduction to the techniques of statistical mechanics for graduate students and researchers in computational biology and biophysics.



  • Material has been reorganized to clarify equilbrium and nonequilibrium aspects of biomolecular systems




  • Content has been expanded, in particular in the treatment of the electrostatic interactions of biomolecules and the application of non-equilibrium statistical mechanics to biomolecules




  • New network-based approaches for the study of proteins are presented.


All treated topics are put firmly in the context of the current research literature, allowing the reader to easily follow an individual path into a specific research field. Exercises and Tasks accompany the presentations of the topics with the intention of enabling the readers to test their comprehension of the developed basic concepts.

Ralf Blossey is a Research Director at the French National Center for Scientific Research, the CNRS, and is based in Lille, in the North of France. His work during the last fifteen years has focussed on the application of statistical mechanics methods to DNA, proteins, gene regulatory networks and chromatin. He has collaborated with many scientists from computer science, mathematics, computational biology, molecular and cellular biology, as well as colleagues from his original field of training, statistical physics.

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