A01=Marc Gilbert
A01=Sergej Pirkmajer
Author_Marc Gilbert
Author_Sergej Pirkmajer
axis
Category=PS
Category=PSAF
cell signaling
cellular biology
eq_bestseller
eq_isMigrated=1
eq_nobargain
eq_non-fiction
eq_science
feedback
immune system
medical history
metabolism
molecular sensors
nervous system
positive and negative signaling ratios and pathways
protein multi-functionality
stem cell differentiation
endocrine system
genetics
molecular biology
organs
Product details
- ISBN 9781786309402
- Weight: 753g
- Publication Date: 13 Sep 2023
- Publisher: ISTE Ltd and John Wiley & Sons Inc
- Publication City/Country: GB
- Product Form: Hardback
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This book provides a comprehensive review of the history of concepts of the endocrine, nervous and immune systems throughout the last century.
Historically, these systems were long considered as compartments that performed separate and different functions. However, a breakthrough occurred when advances in genetics and cellular and molecular biology techniques revealed that these systems shared molecular entities (such as cytokines, hormones and neurotransmitters) with their cognate receptors.
These molecular links between the three systems broaden our understanding of the regulation of physiological processes. This approach has generated a multiplicity of new concepts, including crosstalk between organs, axis, feedback, molecular sensors, protein multi-functionality, positive and negative signaling ratios and pathways (such as cell signaling, metabolism and stem cell differentiation, to name a few).
The improvement of experimental approaches has often resulted in major discoveries. This, combined with clear reasoning, intuition and coherence gave rise to new and unexpected concepts, and sometimes evolving ones. These new concepts lead the reader to the incredible transformation of biology in recent years.
Historically, these systems were long considered as compartments that performed separate and different functions. However, a breakthrough occurred when advances in genetics and cellular and molecular biology techniques revealed that these systems shared molecular entities (such as cytokines, hormones and neurotransmitters) with their cognate receptors.
These molecular links between the three systems broaden our understanding of the regulation of physiological processes. This approach has generated a multiplicity of new concepts, including crosstalk between organs, axis, feedback, molecular sensors, protein multi-functionality, positive and negative signaling ratios and pathways (such as cell signaling, metabolism and stem cell differentiation, to name a few).
The improvement of experimental approaches has often resulted in major discoveries. This, combined with clear reasoning, intuition and coherence gave rise to new and unexpected concepts, and sometimes evolving ones. These new concepts lead the reader to the incredible transformation of biology in recent years.
Marc Gilbert is Professor of Physiology, Metabolism and Cell Biology at Pierre and Marie Curie University, France. His research interests include diabetes and obesity.
Sergej Pirkmajer is Associate Professor of Pathophysiology and Research Group Leader at the Faculty of Medicine, University of Ljubljana, Slovenia. His research interests include the regulation of energy metabolism and ion transport.
