Conformational Proteomics Of Macromolecular Architecture: Approaching The Structure Of Large Molecular Assemblies And Their Mechanisms Of Action (With Cd-rom)

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A01=Lena Hammar
A01=R Holland Cheng
Actin Filament
Atomic Force Microscopy
Author_Lena Hammar
Author_R Holland Cheng
Category=PHVN
Category=PNNP
Category=PSB
Category=PSD
Category=PSG
Crystallography
Cytosceleton
Electron Cryo-Microscopy
Enzymes
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eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
eq_science
Functional Proteomics
Macromoleculars
Ribosomal Structure
Virus Structure

Product details

  • ISBN 9789812386151
  • Publication Date: 22 Jun 2004
  • Publisher: World Scientific Publishing Co Pte Ltd
  • Publication City/Country: SG
  • Product Form: Paperback
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Biological processes involving large macromolecular assemblies are thought to be a dynamic consequence of cooperativity and metastability. The folding of a peptide chain creates local environments from which “activity” can emerge. In the same way, the assembly of large molecular complexes creates dynamic features that would only be feasible in a large construct. The biological implications of such adaptation are explored as it applies to the static quasisymmetry situations, as well as to the dynamics of structural transitions. The current wealth of solved high-resolution complex structures makes this an appropriate time to summarize the state of the art in structural dynamics of living architectures. With contributions by leading scientists in the fields of virology, bacterial flagellum, cytoskeleton, ribosome and giant enzymes, this important book presents cutting-edge knowledge in the various fields of structural proteomics of very large molecular assemblies, with the focus on their mechanisms of action.

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