Controlled Drug Release Of Oral Dosage Forms

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A01=Jean-Maurice Vergnaud
advanced oral drug delivery modelling
Anisotropic materials
Author_Jean-Maurice Vergnaud
biomedical engineering applications
Category=PBKS
controlled release mechanisms
Cylinder of infinite and finite length
Diffusion in Cylinders
drug transport analysis
eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
error function
Finite coefficient
Hollow sphere
Isotropic materials
Isotropic Rectangular Parallelepiped
Mathematical Treatment of Diffusion in a Plane Sheet
numerical simulation pharmacokinetics
pharmaceutical diffusion modelling
Polymer in the glassy state
Polymer in the rubbery state
polymer matrix systems
Radial Diffusion in a Sphere
The Diffusion Equations and Basic Considerations
trigonometrical series
Uniform initial distribution

Product details

  • ISBN 9780131749542
  • Weight: 950g
  • Dimensions: 156 x 234mm
  • Publication Date: 31 Jul 1993
  • Publisher: Taylor & Francis Ltd
  • Publication City/Country: GB
  • Product Form: Hardback
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Numerical analysis of matter transfer is an area that pharmacists find difficult, but which is a technique frequently used in preparing controlled drug release and oral dosage forms. This book provides clear and straightforward information enabling the reader to carry out numerical analysis of matter transfer - a vital processs when looking at the formulation of oral dosage forms with controlled drug release. The drug is dispersed in a polymeric matrix either biodegradable or not, the basis of which is the transfer of the liquid and the drug through dosage form. Information on this diffusion is found either through mathematical treatment when the problem is simple, or through numerical analysis for more complex problems. Professor Vergnaud demonstrates and clarifies these, modelling the process of drug delivery by using numerical analysis and computerization. A simulation of the process is provided, together with a determination of the effects of all parameters, and the author uses both mathematical and numerical models to predict the preparation of new dosage forms able to fulfil specific conditions.

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