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Differentiation of Chiral Compounds Using NMR Spectroscopy

Thomas J. Wenzel
€199.58
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absolute configuration
Author_Thomas J. Wenzel
Axial chiral reagents
Boron-containing reagents
Calixarenes
Category=PNFS
Chiral derivatizing agents
Chiral gels
Chiral liquid crystals
Chiral micelles
Chiral NMR analysis using only instrumental methods
Chiral solvating agents
Crown ethers
Cyclodextrins
database methods
Enantiomeric excess
enantiomeric purity
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Glycoside-based reagents
High-throughput enantiomeric purity measurements
Kinetic resolution catalysts
NMR methods
Paramagnetic lanthanide complexes
Phosphorus-based reagents
Receptor compounds
Resorincarenes
Selection of chiral NMR reagents
Selenium-based reagents
Self-induced diastereomeric anisochronism (SIDA)
Silicon-containing reagents
Solid-state NMR spectroscopy
Transition metal complexes

Product details

  • ISBN 9781119323914
  • Weight: 1429g
  • Dimensions: 180 x 256mm
  • Publication Date: 10 Aug 2018
  • Publisher: John Wiley & Sons Inc
  • Publication City/Country: US
  • Product Form: Hardback
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Description

An updated guide to the most current information available for determining how to use NMR spectroscopy to differentiate chiral compounds 

Differentiation of Chiral Compounds Using NMR Spectroscopy offers a thoroughly revised second edition to the essential volume that puts the focus on the chiral systems that are commercially available and have been widely vetted for use in NMR spectroscopy. The text covers a broad range of reagents that make it possible to determine the enantiomeric purity and assign the absolute configuration of many classes of compounds.

Comprehensive in scope, the text describes the chiral NMR differentiating agents as derivatizing agents, solvating agents, metal-based reagents and liquid crystals and gels, and explains the range and types of compounds for which they can be used for analysis. New to this edition are the most recent findings in the field as well as the development of advanced NMR measurement techniques that allow for the simplification of complex spectra resulting in more readily identified enantiodifferentiation. This important resource:

  • Includes the most recent coverage of a large range of compounds that can be analyzed using chiral NMR reagents
  • Explores the use of chiral NMR reagents and explains their relationship to the stereochemistry of the analyzed molecules
  • Offers the essential information needed to help decide which method is the best NMR method to apply to a class or molecules
  • Contains experimental strategies for using the reagents that are likely to improve the quality of the results

Differentiation of Chiral Compounds Using NMR Spectroscopy is a comprehensive guide designed for investigators planning to use NMR spectroscopy to determine enantiomeric purity or assign the absolute configuration of a compound.
About Thomas J. Wenzel

THOMAS J. WENZEL, PHD, is the Charles A. Dana Professor of Chemistry at Bates College in Lewiston, Maine. He has served terms as chair of the Science Division, Chemistry Department, Biochemistry Program and the interdisciplinary Environmental Studies Program.

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