Guide to Zona Pellucida Domain Proteins
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A01=Eveline S. Litscher
A01=Paul M. Wassarman
amino acids
Author_Eveline S. Litscher
Author_Paul M. Wassarman
Category=PSB
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human pathology
mammalian eggs
zona pellucida domain protein family
ZP domain
ZPDC proteins
Product details
- ISBN 9780470528112
- Weight: 413g
- Dimensions: 160 x 241mm
- Publication Date: 04 Aug 2015
- Publisher: John Wiley & Sons Inc
- Publication City/Country: US
- Product Form: Hardback
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This book provides a coherent, clear, and uniform presentation of structural, genetic, molecular, and biochemical information available for the zona pellucida domain protein family, which impact pathologies such as infertility, deafness, and cancer. Furthermore it:
- Details information about the structure and function of the ZP domain in ZPDC-proteins
- Provides illustrations of the organization of ZPDC-proteins, the genes that encode the proteins, and examples of mutations in the ZP domain that cause diseases
- Speculates as to the evolution of the ZP domain and potential therapeutics for diseases stemming from ZP domain mutations
- Addresses mammalian and non-mammalian systems
Eveline S. Litscher, Ph.D., is Assistant Professor in the Department of Developmental and Regenerative Biology at the Icahn School of Medicine at Mount Sinai in New York City. Previously a Swiss National Science Foundation post-doctoral fellow in the Department of Cell and Developmental Biology at the Roche Institute of Molecular Biology, she has more than 20 years of research experience working on extracellular coat proteins of mammalian and non-mammalian eggs, and has published more than 45 primary papers and reviews.
Paul M. Wassarman, Ph.D., is Professor in the Department of Developmental and Regenerative Biology at the Icahn School of Medicine at Mount Sinai in New York City. Previously a faculty member in the Department of Biological Chemistry at Harvard Medical School and in the Department of Cell and Developmental Biology at the Roche Institute of Molecular Biology, he has more than 35 years of research experience working on extracellular coat proteins of mammalian and non-mammalian eggs, and has published more than 220 primary papers and reviews.
Paul M. Wassarman, Ph.D., is Professor in the Department of Developmental and Regenerative Biology at the Icahn School of Medicine at Mount Sinai in New York City. Previously a faculty member in the Department of Biological Chemistry at Harvard Medical School and in the Department of Cell and Developmental Biology at the Roche Institute of Molecular Biology, he has more than 35 years of research experience working on extracellular coat proteins of mammalian and non-mammalian eggs, and has published more than 220 primary papers and reviews.
