advanced metabolic profiling
Category=PSB
cytochrome
drug-drug interactions
enzyme induction
epoxide
eq_bestseller
eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
eq_science
flavin-containing
glucuronosyltransferase
hydrolase
metabolic pathways
monooxygenase
p450
pharmacology education
studies
toxicology research
udp
xenobiotic
xenobiotic biotransformation
Product details
- ISBN 9780824702298
- Weight: 1290g
- Dimensions: 178 x 254mm
- Publication Date: 29 Mar 1999
- Publisher: Taylor & Francis Inc
- Publication City/Country: US
- Product Form: Hardback
Secure
checkout
Fast Shipping
Easy returns
Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the book provides a framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the importance of pharmacokinetics and cytochrome P450, explains clearance, volume of distribution, sequential metabolism, and nonlinear kinetics, summarizes concepts of Phase 1 and 2 metabolites, evaluates tertiary amine metabolism and reactive metabolite chemistry, and more.
Thomas F. Woolf
