Histones and Other Basic Nuclear Proteins

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A01=Gary S. Stein
A01=Janet L. Stein
Author_Gary S. Stein
Author_Janet L. Stein
biochemical characterization
Category=PSB
chromatin remodeling
chromosomal protein structure analysis
DNA-protein interactions
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eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
eq_science
gene regulation mechanisms
Histone Genes
Human Myeloid
Nuclear Protein
posttranslational modification
spermatogenesis proteins

Product details

  • ISBN 9780849355158
  • Weight: 940g
  • Dimensions: 210 x 280mm
  • Publication Date: 30 Jun 1989
  • Publisher: Taylor & Francis Inc
  • Publication City/Country: US
  • Product Form: Hardback
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This comprehensive book is a compilation of Professor Lubomir S. Hnilica's twenty years of research experimentally addressing the chemistry and the biological functions of chromosomal proteins. The histones and other nuclear proteins found associated with DNA in a number of tissues and cell types are featured. Lubomir Hnilica played a major role in establishing the extent to which these basic chromosomal polypeptides are conserved and the manner in which they interact with DNA to modify chromatin structure. In addition, non-histone chromosomal protein research is explained, and his technique of applying several biochemical and immunological approaches to the characterization of this complex and heterogeneous class of chromosomal polypeptides is discussed. Highlighted is the use of chemical crosslinking for studying protein/DNA interactions in intact cells. The proteins as well as the structure, organization, and regulation of the genes are also presented.

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