Intracellular Calcium-Dependent Proteolysis
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A01=Ronald L. Mellgren
Author_Ronald L. Mellgren
Calcium Dependent Proteinases
calcium-activated protease pathways
Calpain
Calpain Activity
calpain biology
Calpain Ii
Calpain Inhibition
Calpain Substrate
Calpains
Calpastatin Activity
calpastatin inhibitor
Category=PSF
Cysteine Proteinase Inhibitors
Cysteine Proteinases
DEAE Cellulose Column
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Half Maximal Activation
Heavy Chain
Hemostasis
Low Molecular Weight Kininogen
Membrane Skeleton
muscle protein turnover
Myelin Basic Protein
Myofibrillar Proteins
Myosin Heavy Chain
Myosin Light Chain
Myosin Light Chain Kinase
platelet activation mechanisms
Protein
protein catabolism
Protein Kinase
Proteolytically Modified
Rat Erythrocytes
Selenite Cataract
Sepharose CL-2B
Spinal Cord
synaptic plasticity regulation
Product details
- ISBN 9781315894713
- Weight: 720g
- Dimensions: 178 x 254mm
- Publication Date: 13 Dec 2017
- Publisher: Taylor & Francis Ltd
- Publication City/Country: GB
- Product Form: Hardback
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Intracellular Calcium-Dependent Proteolysis explains what is now known about calpains, which are intracellular, non-lysosomal enzymes involved in intracellular protein catabolism. The book provides a comprehensive overview of topics ranging from the molecular biology of the calpains and their specific inhibitor protein (calpastatin) to physiologic and pathologic consequences of the presence of this proteolytic system in many model cells and tissues. Several theoretical functions of the calpains are discussed, including their potential roles in muscle protein turnover, platelet activation, membrane fusion, and synaptic plasticity. Intracellular Calcium-Dependent Proteolysis is a valuable source of information for researchers and students interested in the regulation of intracellular protein catabolism and the general effects of Ca2+ on cell function.
Ronald L. Mellgren, Ph.D., is Associate Professor of Pharmacology and Therapeutics at Medical College of Ohio, Toledo, Ohio.
