ADME Characteristic
AHR Gene
AHR Ligand
Aryl Hydrocarbon Receptor
BD Clontech
biomedical data analysis
Car
Category=PSAG
Category=PSAK
Category=PSAX
cDNA Array
clustering algorithms
Constitutive Androstane Receptor
Diethylnitrosamine Treatment
DNA Damage Agent
DNA Damaging Agent
Drug Metabolism Genes
Endogenous AHR Ligand
eq_bestseller
eq_isMigrated=1
eq_nobargain
eq_non-fiction
eq_science
Expression Profiling Results
gene expression profiling
genomic data interpretation
GREB1
IMR-32 Cells
mechanistic studies
Medium Chain Acyl CoA Dehydrogenase
microarray toxicogenomic research
Oligonucleotide Arrays
Oligonucleotide DNA Microarrays
Parenchymal Hepatocytes
predictive toxicology
Spotted cDNA Arrays
Supplemental Data Section
Toxicogenomic Analysis
Toxicogenomic Studies
Toxicogenomics Databases
Product details
- ISBN 9780367395308
- Weight: 453g
- Dimensions: 178 x 254mm
- Publication Date: 24 Oct 2019
- Publisher: Taylor & Francis Ltd
- Publication City/Country: GB
- Product Form: Paperback
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Since the advent of cDNA microarrays, oligonucleotide array technology, and gene chip analysis, genomics has revolutionized the entire field of biomedical research. A byproduct of this revolution, toxicogenomics is a fast-rising star within toxicological analysis.
Gathering together leading authors and scientists at the forefront of the field, An Introduction to Toxicogenomics provides a comprehensive overview of this new discipline. With a focus on toxicology, it introduces the basic principles of microarray/oligonucleotide array-based genomic analysis and explains how it fits into the field of biomedical research. These discussions provide an overview to the actual mechanics of the analyses themselves and offer insights on handling and quality control. Then the book features an important section on the basics of data analysis and clustering methods such as genetic algorithms. Finally, it covers the application of expression profiling in the field of toxicology and addresses the two fundamental types of analysis in detail, with sections dedicated to both mechanistic and predictive studies.
Although toxicogenomics promises fast, efficient techniques and information-rich data, much of its potential remains untapped. An Introduction to Toxicogenomics consolidates the concepts underlying the field to provide a solid foundation from which to begin your research endeavors.
Michael E. Burczynski
