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Ion and Molecule Transport in Lysosomes

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Alexa Fluor
BK Channel
Blocking Buffer
Category=PSD
Category=PSF
Cell Death and Apoptosis
cell metabolism
Cellular Organelle Function
Conventional Patch Clamp
Endocytic Pathways
Endolysosomal Membranes
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HEK293 Cell
HEK293 Ft Cell
HEK293T Cell
immunological diseases
LMP
Lysosomal Ca
Lysosomal Lumen
Lysosomal Membrane
Lysosomal Transporters
Lysosome Isolation
lysosomes
Melanosomal Proteins
Methionine Synthase
Methylmalonyl CoA Mutase
NAADP
OPTI Mem Medium
Organelle Dysfunction
Patch Clamp
Patch Pipette
Sanger Sequencing Analysis
shRNA Screen
small molecule transporters
Storage Diseases
Transient Receptor Potential Superfamily
waste disposal
Zebrafish Embryos

Product details

  • ISBN 9781138560390
  • Weight: 639g
  • Dimensions: 156 x 234mm
  • Publication Date: 02 Jun 2020
  • Publisher: Taylor & Francis Ltd
  • Publication City/Country: GB
  • Product Form: Hardback
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Description

Lysosomes are key subcellular organelles that regulate the cell function. Many of the essential activities of the cell are dependent on lysosomes. Dysfunction is linked to multiple diseases - storage disorders, neurodegeneration, immunological diseases and cancer. This book discusses concepts and methods used to study lysosome ion and small molecule transport. The contents will not only attract accomplished investigators in need of a broad review and synthesis of this important subject but will also appeal to young investigators and trainees needing to acquire comprehensive knowledge and technical skills working with lysosomal ion channels and small molecule transporters.

Key selling features:

  • Summarizes the endocellular role that lysosomes play with respect to cellular waste disposal
  • Reviews essential cellular functions of lysosomes
  • Explores how lysosome dysfunction is the cause of many metabolic disorders
  • Examines how lysomes are involved in storage diseases
  • Describes various technologies and methods used in lysosome research
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    About
    Bruno Gasnier is CNRS Research Director, Group Leader at CNRS/Paris Descartes. Michael Xi Zhu is currently with the Department of Integrative Biology and Pharmacology at the University of Texas Health Science Center at Houston.