Maspin
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€192.20
A01=Mary J.C. Hendrix
Author_Mary J.C. Hendrix
breast cancer biomarkers
cancer cell invasion
Category=PS
cell-matrix interaction
Cytotrophoblast Invasion
D N A Methylation
Ductal Lobular Units
epigenetic regulation
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eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
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Human Breast Cancer Cell Lines
Human Squamous Carcinoma Cell Lines
integrin modulation
Invasive Breast Cancer
Invasive Breast Cancer Cell Line
Mammary Serine Protease Inhibitor
Maspin Gene
MDA MB-435 Cell
Myoepithelial Cells
Myoepithelial Tumors
Normal Human Breast Epithelial Cells
Normal Human Mammary Epithelial Cells2
Normal Human Peripheral Blood Lymphocytes
Normal Mammary Epithelial Cells
Oral SCC
Primary Breast Cancer Cells
Proc Natl Acad Sci USA
Prostate Specific Ets
RSL
Semiquantitative Rt PCR Analysis
serpin tumor suppressor mechanisms
Silver Stain SDS Page
TIMP-1 Secretion
tumor microenvironment
Urokinase Type Plasminogen Activator
Product details
- ISBN 9781587060977
- Weight: 420g
- Dimensions: 152 x 229mm
- Publication Date: 01 Aug 2002
- Publisher: Taylor & Francis Ltd
- Publication City/Country: GB
- Product Form: Hardback
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This book represents the first compilation of the major research findings regarding Maspin a mammary serpin (or serine) protease inhibitor. Maspin was originally discovered through subtractive hybridization and differential display analyses, comparing the differences in gene expression in normal mammary epithelium and invasive carcinoma cells. This work originated in the laboratory of Dr. Ruth Sager, a world-renowned geneticist, at the Dana Farber Cancer Institute and Harvard Medical School. The first introduction of Maspin to the research community occurred as a report in Science (v263:526-529, 1994), and described the unique tumor-suppressing activity of this novel gene in human mammary epithelial cells.
Mary J.C. Hendrix, Department of Anatomy and Cell Biology Holden Comprehensive Cancer Center The University of Iowa Iowa City, Iowa, U.S.A.
