Cancer
Category=PSAK
Cell
Development
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eq_isMigrated=1
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eq_nobargain
eq_non-fiction
eq_science
Genetics
MicroRNA
miRNA
Small RNA
Product details
- ISBN 9781848163669
- Publication Date: 22 Oct 2010
- Publisher: Imperial College Press
- Publication City/Country: GB
- Product Form: Hardback
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MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer.
