Nitric Oxide, Cell Signaling, and Gene Expression

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26S Proteasomal Degradation
ATP Synthase
ATP Synthesis
Category=PSAK
Category=PSF
cell metabolism regulation
cells
cGMP Dependent Protein Kinase
cGMP Pathway
cGMP Signaling
cgmp-dependent
chain
CNG Channel
Cytochrome Oxidase
endothelial
eq_bestseller
eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
eq_science
factor
HIF 1?
HIF 1α
High Oxidative Stress Level
Hypoxia Inducible Factor-1
IRP1 Activity
mitochondrial
mitochondrial bioenergetics
Mitochondrial CA2
neurovascular research
nitration
nitric oxide gene regulation in disease
Nitroxyl Anion
P38 MAPK
Phd Activity
Phe28 Side Chain
Ras GNE
RAS Superfamily
Ras Superfamily GTPases
redox signaling
respiratory
S-nitrosylation mechanisms
Soluble Guanylyl Cyclase
TfR mRNA
TfR mRNA Level
transcription
Transition Metals
tyrosine
Tyrosine Nitration
vascular biology

Product details

  • ISBN 9780824729608
  • Weight: 732g
  • Dimensions: 152 x 229mm
  • Publication Date: 01 Nov 2005
  • Publisher: Taylor & Francis Inc
  • Publication City/Country: US
  • Product Form: Hardback
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Since the nineteenth century, when engineers were using nitroglycerin to blow up rockbeds, and doctors were prescribing it to relieve angina, scientists have been exploring the incredible and often baffling behavior of nitric oxide. In the 1980s, researchers discovered that nitric oxide had the capacity to regulate vascular tone through cyclic GMP, firmly establishing its role as a physiological mediator. Over the last ten years, still further roles have been discovered that relate to nitric oxide’s unique ability to interact with and modify a wide variety of other molecules and regulators including glutathione, as well as macromolecules such as DNA and proteins.

Nitric Oxide, Cell Signaling, and Gene Expression is the first comprehensive work to showcase the highly useful diversity of cellular effects elicited by nitric oxide. A collection of expert contributors provides cutting-edge information on a variety of topics with tremendous implications in the fields of biology and medicine. These include…

  • Nitric oxide-driven cell signaling mediated by cGMP, GTPases, and S-nitrosylation
  • Nitric oxide’s role in hypoxia, gene expression, post-transcriptional control of gene expression, gene regulation in pulmonary pathophysiology, and tumor biology
  • The intriguing concept of mitochondrial nitric oxide synthase as a regulator of mitochondrial bioenergetics and free radical production
  • Modulation of cell metabolism
  • Nitric Oxide, Cell Signaling, and Gene Expression offers cell and molecular biologists, pharmacologists, biochemists, and biomedical researchers, as well as advanced graduate students, the insight and information they need to understand recent developments in this highly fertile area of research.