Organic Reactions, Volume 77

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Barton-McCombie reaction
carboxylic acid derivatives
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Kulinkovich cyclopropanation
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Organic Reactions
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Product details

  • ISBN 9781118163801
  • Weight: 998g
  • Dimensions: 163 x 236mm
  • Publication Date: 10 Apr 2012
  • Publisher: John Wiley & Sons Inc
  • Publication City/Country: US
  • Product Form: Hardback
  • Language: English
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This new volume in the venerable Organic Reactions series comprises two chapters written in part by the inventors of the unique and important name reactions discussed in these chapters. The first chapter describes a truly remarkable transformation of carboxylic acid derivatives into heteroatom-substituted cyclopropanes, now known as Kulinkovich Cyclopropanation. The second chapter represents an homage to one of the giants of organic chemistry, Sir Derek H. R. Barton. This chapter covers the radical deoxygenation of secondary alcohols that has become known as the Barton-McCombie Reaction.
Scott E. Denmark received his undergraduate degree from the Massachusetts Institute of Technology in 1975 and his graduate degree (D.Sc. Tech.) from the ETH-Zürich in 1980. He joined the faculty at Illinois in the same year. His research interests are in structural, synthetic and mechanistic organic chemistry.