Organic Reactions, Volume 79

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A01=Scott E. Denmark
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asymmetric transformations
Author_Scott E. Denmark
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chiral lithium amides
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cross-coupling reactions of organotrifluoroborate salts
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Organic Reactions
organotrifluoroborate salts
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Suzuki-Miyaura cross-coupling reaction

Product details

  • ISBN 9781118509418
  • Weight: 1043g
  • Dimensions: 163 x 231mm
  • Publication Date: 15 Feb 2013
  • Publisher: John Wiley & Sons Inc
  • Publication City/Country: US
  • Product Form: Hardback
  • Language: English
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Volume 79 in the venerable Organic Reactions series contains two chapters. The first addresses cross-coupling reactions of organotrifluoroborate salts, useful in the development of natural products, materials, and pharmacologically active substances. It is an excellent companion to two previous chapters on tin-based and silicon-based cross-couplings contained in Volumes 50 and 75, respectively. The second chapter addresses asymmetric transformations by deprotonation using chiral lithium amides, useful in target-oriented synthesis, and representing one of the most powerful workhorse reactions in organic synthesis.

Scott E. Denmark received his undergraduate degree from the Massachusetts Institute of Technology in 1975 and his graduate degree (D.Sc. Tech.) from the ETH-Zürich in 1980. He joined the faculty at Illinois in the same year. His research interests are in structural, synthetic and mechanistic organic chemistry.

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