Pharmacogenomics in Admixed Populations
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A01=. G. Suarez-Kurtz
AA Phenotype
ABCB1 Gene
ABCB1 Genotype
ABCB1 Polymorphism
Active CYP2D6 Gene
Admixed Populations
Admixture Proportions
Ancestry Proportions
Author_. G. Suarez-Kurtz
Category=PS
Category=PSAK
clinical pharmacology research
CYP2C19 Genotype Status
CYP2D6 Gene
CYP2D6 Variant Allele
CYP2E1 Polymorphism
CYP3A4 Variant Allele
cytochrome P450 variation
Drug Binding Plasma Protein
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eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
eq_science
ethnic drug response
Gene Dose Dependent Manner
genetic stratification
global health genomics
HIV-1 Protease Inhibitor
Ich E5
Inter-ethnic Differences
Karolinska University Hospital Huddinge
NAT2 Slow Acetylator Phenotype
Organic Anion Transporting Polypeptides
pharmacogenetic diversity analysis
Pharmacogenetic Targets
Plasma Concentration
Pm Frequency
population genetics
Reduced Function Allele
Product details
- ISBN 9781587063114
- Weight: 440g
- Dimensions: 152 x 229mm
- Publication Date: 03 Aug 2007
- Publisher: Taylor & Francis Ltd
- Publication City/Country: GB
- Product Form: Hardback
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Ethnic specificity has become an integral part of research in the overlapping sciences of pharmacogenetics and pharmacogenomics. Pharmacogenomics in Admixed Populations was conceived to compile pharmacogenetic/-genomic (PGx) data from peoples of four continents: Africa, America, Asia and Oceania, where admixture and population stratification occurs in distinct patterns. The organization of this book was formed by a population PGx perspective: an initial review of the evolution of human genetic diversity leads into a series of chapters dealing with the population structure, and the PGx profiles, of various peoples selected on the basis of continents, countries or particular sub-groups within a continent or country.
Dr. G. Suarez-Kurtz, is Head of Pharmacology at the Brazilian National Cancer Institute— INCA— Coordinator of the Brazilian National Pharmacogenomics Network— REFARGEN— and a member of the Committee on Pharmacogenetics of the International Union of Pharmacology— IUPHAR. A pioneer of pharmacogenetic studies in the Brazilian population, his research explores the impact o f genetic admixture on the conceptual development and the praxis of pharmacogenetics/-genomics. He is a Full Member of the Brazilian Academy of Sciences, a Senior Investigator of the Brazilian National Research Council— CNPq— and a Professor of Clinical and Basic Pharmacology at Universidade do Brasil in Rio de Janeiro, where he received his M.D. and Ph.D. degrees. He did postgraduate work at Faculté de Médecine de Paris, Columbia University, New York and University College, London.
