Prion Biology

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Biological Interspecies Barrier in vitro
blot
brain
Category=PSD
Category=PSF
CCI
cellular
cellular mechanisms
diseases
encephalopathies
eq_bestseller
eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
eq_science
experimental neuropathology
Formalin Test
Highly Efficient Protein Misfolding Cyclic Amplification
homogenate
Mechanical Withdrawal Threshold
neurodegenerative diseases
NMDA Receptor
Nociceptive Response
Paw Withdrawal Threshold
prion propagation in mammals
Prion Protein
Prion Protein Self-Peptides Modulate Prion Interactions and Conversion
protein
protein aggregation
protein misfolding
PrP
PrPC Knockout Mice
Prpsc Spreading Patterns in the Brain of Sheep Linked to Different Prion Types
Quantitative Phosphoproteomic Analysis of Prion-infected Neuronal Cells
Spinal Cord
spongiform
transmissible
transmissible spongiform encephalopathies
western

Product details

  • ISBN 9781774632680
  • Weight: 453g
  • Dimensions: 156 x 234mm
  • Publication Date: 31 Mar 2021
  • Publisher: Apple Academic Press Inc.
  • Publication City/Country: CA
  • Product Form: Paperback
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This title includes a number of Open Access chapters.

This book contains a selection of chapters aimed to provide a better understanding prion structure and biology. Together these chapters provide an overview of prion biology and underscore some of the challenges we face if we want to understand how this lively pathogen propagates and evolves in mammals. There is also mounting evidence that studying prion biology has a wider relevance due to similarities in the processes of protein misfolding and aggregation between prion disorders and other neurodegenerative disorders such as Alzheimer’s, Parkinson’s, and Huntington’s diseases.

Dr. Vincent Béringue is working in the prion field for almost twenty years. He has obtained his PhD in 1998 from the AgroParisTech Institute in Paris, in the laboratory of late Dr. Dominique Dormont. After a MRC-funded postdoctoral position in the laboratory of Prof. John Collinge and Dr. Simon Hawke at Imperial College School of Medicine in London, he joined Dr. Hubert Laude’s laboratory at INRA (National Institute for Agricultural Research) in Jouy-en-Josas in 2001, as permanent staff scientist. He is now head of lab in the Molecular Virology Immunology Department at INRA. His primary research interests include the biochemistry, diversity and evolution of animal and human prions.