Protein Geometry, Classification, Topology and Symmetry
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2002a
A01=Andras Aszodi
A01=William R. Taylor
Acetohydroxy Acid Isomeroreductase
advanced protein shape comparison
Author_Andras Aszodi
Author_William R. Taylor
bond
Category=PSB
Cylindrical Barrels
deterministic modeling proteins
Dg
distance
DSSP
DSSP Program
Effective Chain Length
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fold
Fold Space
Globin Fold
hydrogen
Inertial Axes
Jelly Roll
Mandelate Racemase
matrix
molecular geometry methods
protein folding analysis
Protein Structure Comparison
RMS Deviation
Rossmann Fold
secondary
Secondary Structure
Secondary Structure Types
Set Domain
Single Linkage Clustering Algorithm
Solvent Accessible Surface Area
space
SSAP
SSE
structural bioinformatics
structure
Structure Prediction
symmetry in biomolecules
taylor
TIM
TIM Barrel
topological protein structures
Tornado Plots
Product details
- ISBN 9780750309851
- Weight: 800g
- Dimensions: 156 x 234mm
- Publication Date: 01 Oct 2004
- Publisher: Taylor & Francis Ltd
- Publication City/Country: GB
- Product Form: Hardback
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Using a geometric perspective, Protein Geometry, Classification, Topology, and Symmetry reviews and analyzes the structural principals of proteins with the goal of revealing the underlying regularities in their construction. It also reviews computer methods for structure analysis and the automatic comparison and classification of these structures with an analysis of the statistical significance of comparing different shapes. Following an analysis of the current state of protein classification, the authors explore more abstract geometric and topological representations, including the occurrence of knotted topologies. The book concludes with a consideration of the origin of higher-level symmetries in protein structure.
The authors focus on simple geometric methods that are deterministic rather than probabilistic and on the more abstract simplifications of protein structure that allow a better understanding of the overall fold of the structure. Most of the methods described in this book have corresponding computer programs. These can be found (as C source code) at the ftp site of the Division of Mathematical Biology at the National Institute for Medical Research. This collection of ideas contains pedagogical material that make it ideal for post-graduate courses as well as new ideas and results essential for researchers investigating protein structures.
Taylor, William R.; Aszodi, Andras
