Proteomics of Biological Systems
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€164.86
A01=Bryan M. Ham
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Author_Bryan M. Ham
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Blast2GO gene ontology
Category1=Non-Fiction
Category=PNFS
Category=PSB
Category=PSBC
Category=PSE
COP=United States
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Language_English
mass spectrometry and phosphorylation
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phosphate (PO4) group
phosphoproteomic
phosphoproteomic sample preparation
phosphorylation
Price_€100 and above
protein phosphorylation using mass spectrometry
protein phosphorylation using MS
proteomics
PS=Active
softlaunch
Product details
- ISBN 9781118028964
- Weight: 658g
- Dimensions: 160 x 236mm
- Publication Date: 16 Dec 2011
- Publisher: John Wiley & Sons Inc
- Publication City/Country: US
- Product Form: Hardback
- Language: English
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Phosphorylation is the addition of a phosphate (PO4) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group. It also provides a combination of detailed, step-by-step methodology for phosphoproteomic sample preparation, mass spectral instrumental analysis, and data interpretation approaches. Furthermore, it includes the use of bioinformatic Internet tools such as the Blast2GO gene ontology (GO) tool, used to help understand and interpret complex data collected in these studies.
BRYAN M. HAM, PhD, is a member of the American Society for Mass Spectrometry and the American Chemical Society. He has conducted proteomics and lipidomics research at The Ohio State University and Pacific Northwest National Laboratory in Richland, Washington. He is currently working for the Department of Homeland Security at the U.S. Customs and Border Protection New York Laboratory. He has published numerous research papers in peer-reviewed journals, and is the author of Even Electron Mass Spectrometry with Biomolecule Applications (Wiley).
