Product details
- ISBN 9780470192245
- Weight: 794g
- Dimensions: 163 x 244mm
- Publication Date: 15 May 2009
- Publisher: John Wiley & Sons Inc
- Publication City/Country: US
- Product Form: Hardback
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Multidisciplinary perspectives and approaches to quinone methides research
The Wiley Series on Reactive Intermediates in Chemistry and Biology investigates reactive intermediates from the broadest possible range of disciplines. The contributions in each volume offer readers fresh insights into the latest findings, emerging applications, and ongoing research in the field from a diverse perspective.
This inaugural volume in the series, Quinone Methides, represents the first book devoted to this fascinating and useful intermediate. The authors of this work reflect the many disciplines and approaches to quinone methides research. The volume therefore covers a broad range of topics, including theoretical treatments, generation and detection of intermediates, characterization and applications in chemistry and biochemistry, and biological reactivity. Among the chapters are:
- Photochemical generation and characterization of quinone methides
- Quinone methide stabilization by metal complexation
- Self-immolative dendrimers based on quinone methides
- Characterization of quinone methides by spectral global fitting and 13C labeling
- Formation and reactions of xenobiotic quinone methides in biology
- Quinone methides in lignification
With this collection of topics, readers already familiar with quinone methides have the opportunity to advance their own research by discovering new inspiration and opportunities in allied areas. Moreover, the range of topics and perspectives covered make this volume accessible to readers with a broad range of interests, including organic and physical chemistry, biochemistry, biotechnology, and pharmaceutics.
STEVEN E. ROKITA, PhD, is Professor in the Department of Chemistry and Biochemistry at the University of Maryland. His research interests lie in sequence and conformation specific reactions of nucleic acids, enzyme-mediated activation of substrates and coenzymes, halogenation and dehalogenation reactions in biology, aromatic substitution and quinone methide generation in bioorganic chemistry, copper- and nickel-mediated reactions in bioinorganic chemistry, and electron transfer in biopolymers. Dr. Rokita has more than eighty publications and twelve patents on file to his credit.
