Sample Sizes for Clinical, Laboratory and Epidemiology Studies

Regular price €90.99
ordered categorical and continuous outcomes

Guide to Sample Size Tables for Clinical

A01=David Machin
A01=Michael J. Campbell
A01=Say Beng Tan
A01=Sze Huey Tan
Age Group_Uncategorized
Age Group_Uncategorized
Author_David Machin
Author_Michael J. Campbell
Author_Say Beng Tan
Author_Sze Huey Tan
automatic-update
basic design considerations
binary outcomes
Category1=Non-Fiction
Category=MJ
cluster designs
confidence intervals for clinical studies
continuous outcomes
COP=United Kingdom
Delivery_Delivery within 10-20 working days
dual endpoints
eq_isMigrated=2
eq_nobargain
feasibility and pilot studies
further design considerations
genomic targets and dose-finding in clinical studies
Laboratory and Epidemiology Studies
Language_English
more than two groups designs
non-inferiority and equivalence
observer agreement studies
ordered categorical outcomes
PA=Available
paired binary
Price_€50 to €100
PS=Active
randomised and genomic targets
rate outcomes
reference intervals and receiver operating curves

repeated outcome measures
resource for understanding Sample Size Tables for Clinical
softlaunch
stepped wedge designs
survival time
the correlation coefficient
therapeutic exploratory trials - single arm with binary outcomes
therapeutic exploratory trials - survival

Product details

  • ISBN 9781118874943
  • Weight: 816g
  • Dimensions: 191 x 236mm
  • Publication Date: 10 Aug 2018
  • Publisher: John Wiley and Sons Ltd
  • Publication City/Country: GB
  • Product Form: Hardback
  • Language: English
Delivery/Collection within 10-20 working days

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An authoritative resource that offers the statistical tools and software needed to design and plan valid clinical studies

Now in its fourth and extended edition, Sample Sizes for Clinical, Laboratory and Epidemiology Studiesincludes the sample size software (SSS) and formulae and numerical tables needed to design valid clinical studies. The text covers clinical as well as laboratory and epidemiology studies and contains the information needed to ensure a study will form a valid contribution to medical research. 

The authors, noted experts in the field, explain step by step and explore the wide range of considerations necessary to assist investigational teams when deriving an appropriate sample size for their when planned study. The book contains sets of sample size tables with companion explanations and clear worked out examples based on real data. In addition, the text offers bibliography and references sections that are designed to be helpful with guidance on the principles discussed.

This revised fourth edition:

  • Offers the only text available to include sample size software for use in designing and planning clinical studies
  • Presents new and extended chapters with many additional and refreshed examples
  • Includes clear explanations of the principles and methodologies involved with relevant practical examples
  • Makes clear a complex but vital topic that is designed to ensure valid methodology and publishable results 
  • Contains guidance from an internationally recognised team of medical statistics experts

Written for medical researchers from all specialities and medical statisticians, Sample Sizes for Clinical, Laboratory and EpidemiologyStudies offers an updated fourth edition of the important guide for designing and planning reliable and evidence based clinical studies.

David Machin, Leicester Cancer Research Centre, University of Leicester, Leicester and Medical Statistics Group, School of Health and Related Research, University of Sheffield, Sheffield, UK.

Michael J. Campbell, Medical Statistics Group, School of Health and Related Research, University of Sheffield, Sheffield, UK.

Say Beng Tan, SingHealth Duke-NUS Academic Medical Centre, Singapore.

Sze Huey Tan, Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore.