Skeletal Development and Remodeling in Health, Disease and Aging, Volume 1068

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basic
better
biological
bone
Category=PSD
decade
enormously expanded
eq_bestseller
eq_isMigrated=1
eq_nobargain
eq_non-fiction
eq_science
including transgenesis
instances
lay
molecular
new
osteoblasts
past
pathophysiology
pathways
precise
properties
responds
skeleton
source
studies
understanding
us

Product details

  • ISBN 9781573315838
  • Weight: 943g
  • Dimensions: 152 x 231mm
  • Publication Date: 03 Jul 2006
  • Publisher: John Wiley and Sons Ltd
  • Publication City/Country: GB
  • Product Form: Paperback
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Our understanding of how the skeleton is remodeled and repaired has been enormously expanded in the past decade.

Using advanced molecular technologies including transgenesis, gene knockout, and gene array, we are gaining a better understanding of both the precise pathways through which osteoblasts lay down new bone and how osteoclasts remove old bone. These studies have not only helped us understand the basic biological properties of the skeleton and how it responds to hormonal, cytokine, and mechanical stimulation, but also, in some instances, clarified the source of pathophysiology.

The eventual goal of such discoveries is to lay down a firm scientific foundation for the identification of novel cellular and molecular targets for future drug development. This volume presents the significant headway that scientists have made in this undertaking and the book is organized around four broad themes: skeletal development and repair, molecular endocrinology of bone, bone cell biology, and conservation of skeletal integrity. Also included are papers that focus on current and emerging therapies for osteoporosis.

NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.

ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Mone Zaidi is the editor of Skeletal Development and Remodeling in Health, Disease and Aging, Volume 1068, published by Wiley.