Statistical Physics Of Dna: An Introduction To Melting, Unzipping And Flexibility Of The Double Helix
Regular price
€82.99
14 days return policy
Shipping & Delivery
A01=Nikos Theodorakopoulos
Author_Nikos Theodorakopoulos
Category=PHVN
DNA
eq_bestseller
eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
eq_science
Flexibility
Hairpins
Kratky-Porod
KratkyAcAEURA"Porod
Kratky–Porod
Melting
Overstretching
Peyrard-Bishop
PeyrardAcAEURA"Bishop
Peyrard–Bishop
Poland-Scheraga
PolandAcAEURA"Scheraga
Poland–Scheraga
Statistical Mechanics
Statistical Physics
Unzipping
Product details
- ISBN 9789811209536
- Publication Date: 16 Jan 2020
- Publisher: World Scientific Publishing Co Pte Ltd
- Publication City/Country: SG
- Product Form: Hardback
Secure
checkout
Fast Shipping
Easy returns
The stability of the DNA double helix is contingent on fine-tuning a number of physicochemical control parameters. Varying any one of them leads to separation of the two strands, in what constitutes a rare physical example of a thermodynamic phase transition in a one-dimensional system. The present book aims at providing a self-contained account of the statistical physics of cooperative processes in DNA, e.g. thermal and mechanical dissociation, force-induced melting, equilibria of hairpin-like secondary structures. In addition, the book presents some fundamental aspects of DNA elasticity, as observed in key experiments, old and new. The latter include some recently published scattering data on apparently soft, short DNA chains and their interpretation in terms of local structural defects (permanent bends, "kinky DNA", after the original Crick-Klug hypothesis).The development of mathematical models used (Kratky-Porod polymer chain, Poland-Scheraga and Peyrard-Bishop-Dauxois models of DNA melting) emphasizes the use of realistic parameters and the relevance of practical numerical methods for comparing with experimental data. Accordingly, a large number of specially produced figures has been included.The presentation is at the level of an advanced undergraduate or introductory graduate course. An extra chapter provides the necessary mathematical background on elasticity of model polymer chains.
