Home » Structural Genomics and High Throughput Structural Biology
Product Image

Structural Genomics and High Throughput Structural Biology

€80.99
Quantity:
In stock with our UK publisher. 14-28 days
Delivery/Collection within 10-20 working days
14 days return policy Shipping & Delivery
15N HSQC Spectrum
AB INITIO
Ab Initio Folding
advanced protein structure research
alignment
bank
bioinformatics techniques
Category=PSAK
Category=PSB
computational protein analysis
coupling
Crystallization Trials
crystallography automation
data
Data Set
dipolar
Electron Density Map
EMBL Nucleotide Sequence Database
eq_bestseller
eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
eq_science
Free Interface Diffusion
High Throughput Structural Biology
Homology Models
MC
molecular pathway mapping
multiple
Multiple Sequence Alignment
NMR Spectroscopy
NMR Spectrum
NMR Structure Determination
PDB Entry
protein
protein folding mechanisms
protein function annotation
proteome
Ramachandran Plot
RDC
residual
sequence
Structural Biology
Structural Genomics
Structural Genomics Efforts
Structural Proteomics
Structure Determination
Structure Prediction
Unannotated Proteins

Product details

  • ISBN 9780367392239
  • Weight: 426g
  • Dimensions: 156 x 234mm
  • Publication Date: 19 Sep 2019
  • Publisher: Taylor & Francis Ltd
  • Publication City/Country: GB
  • Product Form: Paperback
Secure checkout Fast Shipping Easy returns
Description

Researchers in structural genomics continue to search for biochemical and cellular functions of proteins as well as the ways in which proteins assemble into functional pathways and networks using either experimental or computational approaches. Based on the experience of leading international experts, Structural Genomics and High Throughput Structural Biology details state-of-the-art analytical and computational methods used to reveal the three-dimensional structure and function of proteins.

A historical perspective and a detailed guide to the production of protein material for structural determination, a key step in the process, lay the necessary foundation for discussing the most effective structure determination technologies, such as X-ray crystallography and NMR spectroscopy. Encouraging the study of genes and proteins of unknown structure in order to discover new information about folding, specific structural features, or function, Structural Genomics and High Throughput Structural Biology presents the methods used to interpret the sequences of proteins in a structural context, giving insight into their function. It also explains how to extract information from public data repositories and how to account for variability and accuracy in the quality of this data.

The book concludes with a discussion of practical applications of therapeutically driven structural genomics, and presents future directions in the field. Structural Genomics and High Throughput Structural Biology offers a comprehensive guide to the theoretical, technological, and experimental methodologies used to derive structural information from encoded proteins by renowned and world leading scientists in the field.
About
Michael Sundström, Martin Norin, Aled Edwards