Superoxide Ion Chemistry and Biological Implications
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A01=Igor B. Afanas'ev
Aprotic Solvents
Aqueous Solution
Ascorbic Acid
Author_Igor B. Afanas'ev
Category=PSB
Electrochemical Method
enzymatic radical generation
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eq_isMigrated=1
eq_isMigrated=2
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ESR Spectra
free radical biochemistry
Hydrogen Peroxide
lipid peroxidation pathways
Metal Complexes
nucleic acid oxidation
Organic Compounds
oxidative stress mechanisms
oxygen radical cellular interactions
Photochemical Method
reactive oxygen species
Superoxide Ion
Product details
- ISBN 9780849354519
- Weight: 680g
- Dimensions: 210 x 280mm
- Publication Date: 31 Aug 1989
- Publisher: Taylor & Francis Inc
- Publication City/Country: US
- Product Form: Hardback
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The chemical properties of superoxide ion, its biological role, and the role of other oxygen radicals which arise as a result of its transformations are contained in this text. In Volume I the principal reactions of superoxide ion, including protonation reactions with proton donors, nucleophilic reactions with esters, alkyl halides and other compounds, electron transfer reactions with quinones and metal complexes, are described. Basic quantitative data including rate constants and yields for the reactions of superoxide ion of all types are given in tables. This volume contains the mechanisms of the generation of oxygen radicals in cells and the interaction of superoxide ion with cell components. The role of superoxide ion in lipid peroxidation and destruction of proteins and nucleic acids is explained, as well as oxygen radicals in the mechanisms of toxic and therapeutic action of drugs, especially anticancer antibiotics. In addition, the action of superoxide ion and other oxygen radicals on plants, micro-, and macroorganisms is discussed, along with the role of oxygen radicals in normal metabolic and pathological processes.
Igor B. Afanas'ev (All-Union Vitamin Research Institute, Moscow, Russia) (Author)
