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A01=Christopher N. Eichelberger
A01=Kayvan Najarian
A01=Shahriar Gharibzadeh
A01=Siamak Najarian
AB INITIO Method
alignment
amino
approach
Author_Christopher N. Eichelberger
Author_Kayvan Najarian
Author_Shahriar Gharibzadeh
Author_Siamak Najarian
bayesian
Bayesian Networks
binary and bayesian networks
biological data analysis
BLOSUM Matrice
Category=UY
computational modeling in biomedical research
Computational Structural Biology
Data Set
DNA Data Bank
DNA Microarray
DNA Microarray Data
DNA Sequence
DNA Sequence Comparison
DNA Strand
eq_bestseller
eq_computing
eq_isMigrated=1
eq_isMigrated=2
eq_nobargain
eq_non-fiction
Galactose Pathway
gene
Gene Network
Gene Protein Interaction
gene silencing
genomics and proteomics
high-throughput experiment methods
Human Genome Sequencing Center
HUPO Proteomics Standard Initiative
interactions
Mason's Rule
Metabolic Control Theory
Microarray Gene Expression Data Society
molecular imaging techniques
Multiple Sequence Alignment
network
Nonlinear Factor Analysis
Nonlinear Model
Pairwise Sequence Alignment
Posttranscriptional Gene Silencing
protein
protein interaction networks
Query Sequence
rational drug design strategies
regulatory
regulatory pathway modeling
sequence
Sequence Alignment

Product details

  • ISBN 9781420046502
  • Weight: 476g
  • Dimensions: 156 x 234mm
  • Publication Date: 13 Apr 2009
  • Publisher: Taylor & Francis Inc
  • Publication City/Country: US
  • Product Form: Hardback
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The availability of molecular imaging and measurement systems enables today’s biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods used in what is being coined the digital era of biology.

Written by field experts with proven track records, this authoritative textbook first provides an introduction to systems biology and its impact on biology and medicine. The book then reviews the basic principles of molecular and cell biology using a system-oriented approach, with a brief description of the high-throughput biological experiments that produce databases.

The text includes techniques to discover genes, perform nucleotide and amino acid sequence matching, and estimate static gene dynamic pathways. The book also explains how to use system-oriented models to predict the behavior of biological systems for important applications such as rational drug design.

The numerous examples and problem sets allow students to confidently explore practical systems biology applications using real examples with real biological data, making Systems Biology and Bioinformatics: A Computational Approach an ideal text for senior undergraduate and first-year graduate students.

Kayvan Najarian, Siamak Najarian, Shahriar Gharibzadeh, Christopher N. Eichelberger

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