Topology and Physics of Circular DNA (1992)
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A01=Alexander Vologodskii
Author_Alexander Vologodskii
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Biophysicists
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Category=PSB
Category=PSD
Circular DNA
Circular DNA Molecule
Circular DNAs
conformational transitions
Constraints
Cruciform Structures
Cyclization
DNA Double Helix
DNA Length
DNA Molecule
DNA Region
DNA supercoiling
Double Helix
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experimental analysis of DNA structure
Free Jointed Chain
GC Pair
knot theory biology
Linear DNA
Linear DNA Molecule
Linking Number
molecular biophysics
Negative Supercoiling
noncanonical
Noncanonical Structures
nucleic acid topology
pBR322 DNA
Persistence Length
Ribbon Axis
Statistical Mechanical Treatment
Statistical Segments
Supercoiled DNA
Supercoiling
Superhelical Density
topoisomerase enzymes
Torsional Stress
Product details
- ISBN 9781138562813
- Weight: 453g
- Dimensions: 156 x 234mm
- Publication Date: 28 Jan 2019
- Publisher: Taylor & Francis Ltd
- Publication City/Country: GB
- Product Form: Paperback
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Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.
Alexander V. Vologodskii is Research Professor of Chemistry Department of Chemistry New York University.
