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A01=and Medicine
A01=Division on Earth and Life Studies
A01=Engineering
A01=Institute for Laboratory Animal Research
A01=National Academies of Sciences
A01=Roundtable on Science and Welfare in Laboratory Animal Use
Age Group_Uncategorized
Age Group_Uncategorized
Author_and Medicine
Author_Division on Earth and Life Studies
Author_Engineering
Author_Institute for Laboratory Animal Research
Author_National Academies of Sciences
Author_Roundtable on Science and Welfare in Laboratory Animal Use
automatic-update
B01=Erin Hammers Forstag
B01=Lida Anestidou
Category1=Non-Fiction
Category=PS
COP=United States
Delivery_Delivery within 10-20 working days
Language_English
PA=Available
Price_€50 to €100
PS=Active
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Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine: Proceedings of a Workshop

Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop.

Table of Contents
  • Front Matter
  • 1 Introduction to Precision Medicine and Animal Models
  • 2 Existing Precision Medicine Initiatives
  • 3 The Promise and Perils of Animal Models
  • 4 Reproducibility and Predictivity
  • 5 In Vitro Alternatives to Animal Models
  • 6 Assessing Safety and Toxicology
  • 7 Patient Perspectives
  • 8 Reflections on the Workshop
  • References
  • Appendix A: Agenda
  • Appendix B: Planning Committee Biographies
  • Appendix C: Speaker Biographies
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A01=and MedicineA01=Division on Earth and Life StudiesA01=EngineeringA01=Institute for Laboratory Animal ResearchA01=National Academies of SciencesA01=Roundtable on Science and Welfare in Laboratory Animal UseAge Group_UncategorizedAuthor_and MedicineAuthor_Division on Earth and Life StudiesAuthor_EngineeringAuthor_Institute for Laboratory Animal ResearchAuthor_National Academies of SciencesAuthor_Roundtable on Science and Welfare in Laboratory Animal Useautomatic-updateB01=Erin Hammers ForstagB01=Lida AnestidouCategory1=Non-FictionCategory=PSCOP=United StatesDelivery_Delivery within 10-20 working daysLanguage_EnglishPA=AvailablePrice_€50 to €100PS=Activesoftlaunch
Delivery/Collection within 10-20 working days
Product Details
  • Dimensions: 152 x 229mm
  • Publication Date: 29 Jun 2018
  • Publisher: National Academies Press
  • Publication City/Country: United States
  • Language: English
  • ISBN13: 9780309471169

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