Recent years have witnessed an increasing number of theoretical and experimental contributions to cancer research from different fields of physics, from biomechanics and soft-condensed matter physics to the statistical mechanics of complex systems. Reviewing these contributions and providing a sophisticated overview of the topic, this is the first book devoted to the emerging interdisciplinary field of cancer physics. Systematically integrating approaches from physics and biology, it includes topics such as cancer initiation and progression, metastasis, angiogenesis, cancer stem cells, tumor immunology, cancer cell mechanics and migration. Biological hallmarks of cancer are presented in an intuitive yet comprehensive way, providing graduate-level students and researchers in physics with a thorough introduction to this important subject. The impact of the physical mechanisms of cancer are explained through analytical and computational models, making this an essential reference for cancer biologists interested in cutting-edge quantitative tools and approaches coming from physics.
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Product Details
Weight: 540g
Dimensions: 178 x 253mm
Publication Date: 20 Apr 2017
Publisher: Cambridge University Press
Publication City/Country: United Kingdom
Language: English
ISBN13: 9781107109599
About Caterina A. M. La PortaStefano Zapperi
Caterina A. M. La Porta is Associate Professor of General Pathology at Università degli Studi di Milano and group leader of the Molecular Oncology Laboratory there. In 2015 she founded the university's Center for Complexity and Biosystems. She has organized several interdisciplinary workshops on the physics of cancer funded by the European Center for Atomic and Molecular Calculations (CECAM) and the European Science Foundation (ESF). Stefano Zapperi is Professor of Theoretical Physics at Università degli Studi di Milano where he coordinates the Center for Complexity and Biosystems and Research Leader at the Institute for Scientific Interchange (ISI) Foundation in Turin Italy. He is an expert in the statistical mechanics of non-equilibrium complex systems and has worked in fracture plasticity friction magnetism and biophysics. He is the recipient of numerous awards and is currently the chairman of the steering committee of the Conference on Complex Systems.