This book provides an overview of various drug delivery systems at the cellular level including biological, chemical methods, and most importantly physical methods such as photoporation, electroporation, mechanoporation, and device-based techniques (e.g., microfluidics), as well as organism-level techniques including nanomaterials, biomaterials, and transdermal. Drug delivery (DD) can be defined as the method and route by which an active pharmaceutical ingredient (API) is administered to promote its desired pharmacological effect and/or convenience and/or to reduce adverse effects. Drug delivery systems are developed to maximize drug efficacy and minimize side effects. As drug delivery technologies improve, the drug becomes safer and more comfortable for patients to use. During the last seven decades, extraordinary progress has been made in drug delivery technologies, such as systems for long-term delivery for months and years, localized delivery, and targeted delivery. The advances, however, will face the next phase considering the future technologies that we need to overcome many physicochemical barriers for new formulation development and biological unknowns for treating various diseases. Thus, various technologies are built at a single-cell level as well as an organism level. This book is useful at the university level for graduate courses or research studies and biotechnology-based companies with research and development on cell-based analysis, diagnosis, or drug screening. This book is also very useful for researchers in drug delivery technologies, which came in frontier research for the past decade.
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Product Details
Dimensions: 155 x 235mm
Publication Date: 29 Nov 2023
Publisher: Springer Verlag Singapore
Publication City/Country: Singapore
Language: English
ISBN13: 9789819965632
About
Dr. Tuhin Subhra Santra is an Associate Professor in the Department of Engineering Design at the Indian Institute of Technology Madras India from July 2016. He was tenure track Honorary Visiting Professor at National Tsing Hua University Taiwan from 2108~2020 and he was Visiting Professor at the University of Cambridge the UK in 2019. Dr. Santra received his Ph.D. degree in Bio-Nanoelectro Mechanical Systems (Bio-NEMS) from National Tsing Hua University in 2013. Dr. Santra was Post-doctoral Researcher at the California Nano System Institute (CNSI) University of California Los Angeles (UCLA) the USA from 2015~2016. His main research areas are Bio-NEMS MEMS Single Cell Single Molecule Detection Biomedical Micro-/Nanodevices Nanomedicine etc. Currently Dr. Santra serves as Guest Editor for Cell and Micromachines MDPI Journals. He served as Guest Editor for the Journal of Cells MDPI in 2020 International Journal of Molecular Science (IJMS) in 2018 2017 and 2015 and Sensors Journal in 2016 Journal of Molecules in 2016 Micromachines in 2020 and 2013 among others. He was Conference Chair and Committee Member of IEEE-NEMS in 2017 2020 and 2021. Dr. Santra has received many honors and awards such as Wellcome Trust/DBT India Alliance Fellowship in 2018 Honorary Research Fellow from National Tsing Hua University Taiwan in 2018 Bharat Bikas Award in 2017 IEEE-NEMS best conference paper award in 2014 and a silver medal from Vidyasagar University in 2004. He was Editor of the book entitled Nanomaterials and Their Biomedical Applications by Springer Nature Singapore in 2021 Handbook of Single-cell technologies by Springer Nature Singapore 2021 Microfluidics and Bio-NEMS: Devices and Applications by Jenny Stanford Publisher Singapore in 2020 and Essential of Single-Cell Analysis Springer Germany in 2016 among others. He published more than 8 books 40 SCI journals 20 book chapters 20 US/Taiwan/Indian patents and 20 international conference proceedings in his research field. Currently he is serving as Book Editor entitled Single-Biomolecules Detection and Analysis by CRC press.Dr. Ashwini Uma Surendra Shinde earned her Ph.D. in Biotechnology from The Institute of Science Mumbai India in 2021 specializing in the green synthesis of diverse metal and polymeric nanoparticles and their potential against cancer cells. Currently Dr. Shinde holds a post-doctoral position under the mentorship of Dr. Tuhin Subhra Santra. Her primary research sphere encompasses bio-nanotechnology and pioneering physical methods of drug delivery systems. Her significant contributions extend to the publication of 8 research articles in prestigious SCI Journals along with 4 review articles and 4 book chapters. Furthermore her innovative work has culminated in the securing of 5 Indian Patents.