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B01=Jacek Z. Kubiak
B01=Malgorzata Kloc
B01=Marta Halasa
Category1=Non-Fiction
Category=MJCL
Category=MJCM
Category=MMFM
Category=PSC
Category=TCB
Category=TGB
COP=Switzerland
Delivery_Pre-order
Language_English
PA=Not yet available
Price_€100 and above
PS=Forthcoming
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Monocytes and Macrophages in Development, Regeneration, and Disease

English

The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs.

Following the great success of Volume 62: Macrophages - Origin, Functions and Biointervention published in this series, this new book now focuses on the role of monocytes and macrophages in development, regeneration and disease. This new volume offers an overview of the latest developments in monocyte and macrophage subtypes and functions across various tissues including adipose tissue, bones, liver, lungs, testes, and the nervous system.

The book also reviews existing and potential therapies targeted towards the macrophages and describes their homeostatic functions. It explores how macrophage cell cycle, metabolism, mitochondrial activity, histone acetylation status, and interaction with the extracellular matrix contribute to changes in macrophage phenotype and function in health and disease. Additionally, it examines the interactions between macrophages and cancer cells, bacteria, helminth parasites, and their role in the colonization and spread of HIV.

For ease of reference, the volume is divided into three sections:

  • Part I Nonimmunologic and immunologic functions of monocytes/macrophages
  • Part II Tissue/organ specific functions of macrophages
  • Part III Macrophage functions and dysfunction in diseases

This book will be of interest to researchers working in the fields of developmental biology, immunology, cancer research, and therapeutic applications. It is written to inform and inspire experts and newcomers to the field of macrophages.

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Current price €183.34
Original price €192.99
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Age Group_Uncategorizedautomatic-updateB01=Jacek Z. KubiakB01=Malgorzata KlocB01=Marta HalasaCategory1=Non-FictionCategory=MJCLCategory=MJCMCategory=MMFMCategory=PSCCategory=TCBCategory=TGBCOP=SwitzerlandDelivery_Pre-orderLanguage_EnglishPA=Not yet availablePrice_€100 and abovePS=Forthcomingsoftlaunch

Will deliver when available. Publication date 21 Nov 2024

Product Details
  • Dimensions: 155 x 235mm
  • Publication Date: 21 Nov 2024
  • Publisher: Springer International Publishing AG
  • Publication City/Country: Switzerland
  • Language: English
  • ISBN13: 9783031659430

About

Dr. Malgorzata Kloc: Prior to completing her postdoctoral training in Canada Dr. Kloc was a tenured Associate Professor in the Department of Zoology at the University of Warsaw Poland. She also served as a Research Associate in the Department of Biology at Carleton University in Ottawa Canada. While completing her postdoctoral training Dr. Kloc earned the AHFMR Research Award from the University of Calgary and the MRC Biotechnology Training Award from Dalhousie University. She joined the University of Texas M.D. Anderson Cancer Center as a Research Scientist in the Department of Molecular Genetics in 1987 and became an Associate Professor in the Department of Biochemistry and Molecular Biology there in 2006. Dr. Kloc joined the Houston Methodist Research Institute in 2008. Currently Dr. Kloc is the Weill Cornell Professor of Cell and Molecular Biology at The Houston Methodist Hospital and the Adjunct Professor at Department of Genetics University ofTexas M D Anderson Cancer Center. Dr. Jacek Z. Kubiak is the Research Director (Professor) at the French National Research Institute CNRS in Rennes France. His research is devoted to molecular mechanisms of early embryo development cell cycle regulation stem cells cancer cells and the role of macrophages in the innate immune response. He is the author of over 180 highly cited scientific articles and the editor or co-editor of 10 books. He has graduated from the Warsaw University Poland and worked at the University of Wisconsin-Madison USA Marine Biological Laboratory in Woods Hole USA and in Jacques Monod Institute in Paris France. He collaborates with research institute WIM-PIB in Warsaw Poland combining stem cells wound healing and cancer research with the prospective in medical applications. Since the COVID-19 outbreak he co-ordinates an international research group focused on SARS-CoV-2 infection in paediatric patients and he follows up this research field. Marta Halasa earned her PhD in medical and health science from the Medical University of Lublin Poland in 2022. Her research during her doctoral studies focused on epigenetic modifiers particularly histone deacetylases and their impact on cancer progression and metastasis. During her PhD she completed a long-term internship at the University of Turku Finland where she gained expertise in 3D cell techniques. She also undertook an internal internship at the Military Institute of Medicine in Warsaw Poland where she investigated cell-gene therapy in Alzheimer's disease. After completing her PhD she obtained a postdoctoral fellow position at the Houston Methodist Research Institute USA. Currently her research focuses on investigating the role of macrophages in chronic transplant rejection. 

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