Microbial Toxins

About

Prof. P. Gopalakrishnakone M.B.B.S. Ph.D. F.A.M.S. D.Sc. is presently professor of anatomy and chairman of the Venom and Toxin Research Programme at Yong Loo Lin School of Medicine National University of Singapore. He is also a consultant to the Defence Science Organization in Singapore and adjunct senior research scientist at the Defence Medical Research Institute. Prof. Gopalakrishnakone is an honorary principal fellow at the Australian Venom Research Unit University of Melbourne Australia. His research studies include structure function studies toxin detection biosensors antitoxins and neutralization factors toxicogenomics and expression studies antimicrobial peptides from venoms and toxins and PLA2 inhibitors as potential drug candidates for inflammatory diseases. The techniques he employs include quantum dots to toxinology computational biology microarrays and protein chips. Prof. Gopalakrishnakone has more than 160 international publications four books about 350 conference presentations and 10 patent applications. He has been an active member of the International Society on Toxinology (IST) for 30 years and was president from 2008 to 2012. He is also the founder president of its Asia Pacific Section a council member as well as an editorial board member of Toxicon the society''''s official journal. His research awards include the Outstanding University Researcher Award from the National University of Singapore (1998); Ministerial Citation NSTB Year 2000 Award in Singapore; and the Research Excellence Award from the Faculty of Medicine at NUS (2003). His awards in teaching include Faculty Teaching Excellence Award 2003/4 and NUS Teaching Excellence Award 2003/4. Prof. Gopalakrishnakone also received the Annual Teaching Excellence Award in 2010 at both university and faculty levels.Dr. Brad Stiles is a microbiologist by training with a keen appreciation for diverse topics in biology. His education in science was formally forged at Pennsylvania State University Virginia Tech and then the University of Texas. He spent over two decades in a Department of Defense laboratory studying protein toxins from snakes marine cone snails and bacteria. The goals were to further a basic understanding of how toxins affect cells and subsequently generate methods for detection as well as neutralization via vaccines therapeutic antibodies and small molecular-weight inhibitors. Results from his laboratory led to numerous peer-reviewed publications with various national and international laboratories. National and international students have studied in his laboratory and now further the tradition of understanding science. Besides working in the United States he has formally studied in France and Germany at various universities and public/private laboratories. Dr. Stiles now teaches microbiology and basic biology courses at Wilson College as well as Shippensburg University both in the US.Alberto Alape-Giron is a professor at the Department of Biochemistry Faculty of Medicine University of Costa Rica and head of Instituto Clodomiro Picado also at University of Costa Rica. Prof. Alape-Giron received his Ph.D. from the Karolinska Institute in Stockholm Sweden and participates as a lecturer in biochemistry undergraduate and graduate courses at the University of Costa Rica. His research interests include bacterial and snake venom toxic proteins. Prof. Alape-Giron is associate editor of FEBS Open Bio and serves as a reviewer for several journals including mBio BBA PLOS One Vaccine and Toxicon.Dr. J. Daniel Dubreuil received a B.Sc. (Agr.) from Macdonald College (McGill University) a master''''s degree from l''''Universite de Montreal and a Ph.D. (Department of Microbiology and Immunology Universite de Montreal) executed at the Armand-Frappier Institute. A year postgraduate study was conducted at the Pasteur Institute in Paris France (Unite des agents antibacteriens) and two in the Department of Biochemistry and Microbiology (Victoria University British Columbia Canada). He joined the Faculty of Veterinary Medicine of the Universite de Montreal in 1988.He was awarded the title of full professor in 1998. In 2001-2002 he was visiting scholar at the Instituto di Ricerche in Immunobiologiche Siena-Chiron a pharmaceutical research center in Siena Italy. There he conducted research on the virulence of Helicobacter pylori. He is the author of over 120 scientific publications including many reviews and several book chapters on Escherichia coli toxins. Very involved with the Canadian Society of Microbiologists he was elected president (2013-2014). Since June 2014 he is chair of the Department of Pathology and Microbiology Faculty of Veterinary Medicine Universite de Montreal.Dr. Manas Mandal received both bachelor''''s (honours) and master''''s degrees in human phyiology from the University of Calcutta India. He earned a Ph.D. degree from the Jadavpur University Calcutta in 1992 working on snake venom vaccine development project at the Calcutta School of Tropical Medicine and Indian Institute of Chemical Biology. Afterwards he did extensive post-doctoral research in cellular immunology at the Gwen Knapp Center for Lupus and Immunology Research University of Chicago and University of Michigan College of Pharmacy. At the University of Michigan he research centered on Listeria monocytogenes-derived toxin listeriolysin-O in a liposomal delivery system targeting antigen-specific protective cytotoxic T lymphocyte response using murine tumor and viral infection models. Dr. Mandal joined Roseman University of Health Sciences College of Pharmacy in 2006 as an assistant professor to direct and coordinate immunology course for the Pharm.D. students. He also teaches immunology to the students of Roseman University College of Dental Medicine. Dr. Mandal is an adjunct faculty position at the Touro University of Nevada and teaches in their Physician''''s Assistant Program and Doctor of Osteopathic Medicine program. He has published in major journals in toxinology immunology and drug delivery. His current research interest involves use of bacterial toxin in vaccine delivery marine toxin in drug discovery and drug-induced immune modulation.